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論文・その他(図書・総説） 2019年度

論文　|　その他(総説・図書）

論文

No. タイトル・発表者等 発表機関
  Poly(N-isopropylacrylamide)-based polymer inducing isothermal hydrophilic-to-hydrophobic phase transition via detachment of hydrophilic acid-labile moietyS.E. Muttaqien, T. Nomoto, H. Takemoto, M. Matsui, K. Tomoda, N. NishiyamaBiomacromolecules10.1021/acs.biomac.8b01465(2018/12) 東京工業大学、iCONM
  In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancersSumiyo Watanabe, Kotaro Hayashi, Kazuko Toh, Hyun Jin Kim, Xueying Liu, Hiroyuki Chaya, Shigeto Fukushima, Keisuke Katsushima, Yutaka Kondo, Satoshi Uchida, Satomi Ogura, Takahiro Nomoto, Hiroyasu Takemoto, Horacio Cabral, Hiroaki Kinoh, Hiroyoshi Y. Tanaka, Mitsunobu R. Kano, Yu Matsumoto, Hiroshi Fukuhara, Shunya Uchida, Masaomi Nangaku, Kensuke Osada, Nobuhiro Nishiyama, Kanjiro Miyata, Kazunori KataokaNature Communications10.1038/s41467-019-09856-w(2019/4/24) iCONM、東京大学、東京工業大学
  Anti‑tissue factor antibody‑mediated immuno‑SPECT imaging of tissue factor expression in mouse models of pancreatic cancer.Sugyo A et alOncol Rep10.3892/or.2019.7017(2019/4) 量子科学技術研究開発機構放射線医学総合研究所、国立がん研究センター
  Usefulness of serum microRNA as a predictive marker of recurrence
and prognosis in biliary tract cancer after radical surgery.Akazawa Y, Mizuno S, Fujinami N, Suzuki T, Yoshioka Y, Ochiya T, Nakamoto Y,Nakatsura T.Sci Rep.10.1038/s41598-019-42392-7(2019/4)		 東京医科大学
  Electrical characterization of electrolyte/β- Ga2O3 junction for biosensing applicationsT. Rahman, T. Masui, T. IchikiJournal of The Electrochemical Society10.1149/2.0501906jes(2019/4) The University of Tokyo
  "Redox Imaging" to Distinguish Cells with Different Proliferative Indexes: Superoxide, Hydroperoxides, and Their Ratio as Potential BiomarkersZhelev Z, Georgieva E, Lazarova D, Semkova S, Aoki I, Gulubova M, Higashi T, Bakalova R.Oxid Med Cell Longev10.1155/2019/6373685(2019/4) National Institutes for Quantum and Radiological Science and Technology (QST),
  Chemically-modified miR-143 exhibited an anti-cancer effect via down-regulation of K-RAS signaling networks of renal cell cancer cells in vitro and in vivoT. Takai, T. Tsujino, Y. Yoshikawa, T. Inanoto, N. Sugito, Y. Kuranaga, K. Heishima, T. Soga, K. Hayashi, K. Miyata, K. Kataoka, H. Azuma, Y. AkaoMol Ther.10.1016/j.ymthe.2019.03.004(2019/5/8) The University of Tokyo, Innovation Center of NanoMedicine, Policy Alternatives Research Institute
  Glucose transporter 1-mediated vascular translocation of nanomedicines enhances accumulation and efficacy in solid tumorsK. Suzuki, Y. Miura, Y. Mochida, T. Miyazaki, K. Toh, Y. Anraku, V. Melo, X. Liu, T. Ishii, O. Nagano, H. Saya, H. Cabral, K. KataokaJournal of Controlled Release 10.1016/j.jconrel.2019.02.021(2019/5/10) The University of Tokyo, Innovation Center of Nanomedicine (iCONM), Keio University, Policy Alternatives Research Institute
  Precise tuning of disulphide crosslinking in mRNA polyplex micelles for optimising extracellular and intracellular nuclease tolerabilityA. Dirisala, S. Uchida, T. A. Tockary, N. Yoshinaga, J. Li, S. Osawa, L. Gorantla, S. Fukushima, K. Osada, K. KataokaJournal of Drug Targeting10.1080/1061186X.2018.1550646(2019/5/15) Innovation Center of NanoMedicine (iCONM), The University of Tokyo, University of Washington, National Institutes for Quantum and Radiology Science and Technology, Policy Alternatives Research Institute
  Sonodynamic Therapy With Anticancer Micelles and High-Intensity Focused Ultrasound in Treatment of Canine Cancer.Yuki Horise, Masanori Maeda, Yoshiyuki Konishi, Jun Okamoto, Soko Ikuta, Yoshiharu Okamoto, Hiroshi Ishii, Shin Yoshizawa, Shinichiro Umemura, Tsuyoshi Ueyama, Satoshi Tamano, Atsushi Sofuni, Kazuhisa Takemae, Ken Masamune, Hiroshi Iseki, Nobuhiro Nishiyama, Kazunori Kataoka, Yoshihiro Muragaki.Frontiers in Pharmacology10.3389/fphar.2019.00545(2019/5/21) 東京女子医科大学、興和株式会社、東京工業大学、iCONM
  Amido-bridged nucleic acid (AmNA)-modified antisense oligonucleotides targeting α-synuclein as a novel therapy for Parkinson's diseaseTakuya Uehara,Chi-Jing Choong,Masayuki
Nakamori,Hideki Hayakawa, Kumiko Nishiyama,Yuuya Kasahara,Kousuke Baba,Tetsuya Nagata,Takanori Yokota,Hiroshi Tsuda,Satoshi Obika,Hideki Mochizuki,Scientific Reports10.1038/s41598-019-43772-9(2019/5)		 東京医科歯科大学
  Optimization of tris(2-carboxyethyl) phosphine reduction conditions for fast analysis of total biothiols in mouse serum samplesChunfang Chang, Muneki Isokawa, Takashi Funatsu, Makoto TsunodaHeliyon10.1016/j.heliyon.2019.e01598(2019/5) 東京大学
  Pyruvate responsiveness based on α-oxohydrazone formation for intracellular siRNA release from polyion complex-based carriers.H. Takemoto, C.L. Wang CL, T. Nomoto, M. Matsui, K. Tomoda, N. NishiyamaBiomacromolecules10.1021/acs.biomac.9b00261(2019/5) 東京工業大学、iCONM
  Cationic comb-type copolymer as an artificial chaperoneO. Hanpanich, A. MaruyamaPolym J10.1038/s41428-019-0210-7(2019/5) 東京工業大学
  Function of Epirubicin-Conjugated Polymeric Micelles in Sonodynamic Therapy.Kazuhisa Takemae, Jun Okamoto, Yuki Horise, Ken Masamune, Yoshihiro Muragaki.Frontiers in Pharmacology10.3389/fphar.2019.00546(2019/5) 東京女子医科大学、興和株式会社
  Characterization of Antibody Products Obtained through Enzymatic and Nonenzymatic Glycosylation Reactions with a Glycan Oxazoline and Preparation of a Homogeneous Antibody-Drug Conjugate via Fc N-Glycan. Manabe SBioconjug Chem.10.1021/acs.bioconjchem.9b00132(2019/5) 理化学研究所、国立がん研究センター
  Development and Validation of an Esophageal Squamous Cell Carcinoma Detection Model by Large-Scale MicroRNA Profiling.Sudo K, Kato K, Matsuzaki J, Boku N, Abe S, Saito Y, Daiko H, Takizawa S,Aoki Y, Sakamoto H, Niida S, Takeshita F, Fukuda T, Ochiya T.JAMA Netw Open.10.1001/jamanetworkopen.2019.4573(2019/5) 東京医科大学
  Rapid increase in transparency of biological organs by matching refractive index of media to cell membrane using phosphoric acidMasakazu Umezawa, Shinsuke Haruguchi, Rihito Fukushima, Shota Sekiyama, Masao Kamimura, Kohei SogaRSC ADV10.1039/C9RA01445D(2019/5) 東京理科大学
  Mechanical strength evaluation of crystalline poly (L-lactic acid) fabricated by replica micromolding for bioabsorbable microneedle devicesY. Kanda, H. Takehara, T. IchikiJapanese Journal of Applied Physics10.7567/1347-4065/ab0ff6(2019/5) University of Tokyo, Innovation Center of NanoMedicine
  Plasma-assisted electrospray deposition of thin elastomer filmsK. Hashimoto, H. Takehara, T. IchikiJapanese Journal of Applied Physics10.7567/1347-4065/ab0ff7(2019/5) University of Tokyo, Innovation Center of NanoMedicine
  Nitroxide-enhanced magnetic resonance imaging of kidney dysfunction in vivo based on redox-imbalance and oxidative stressLazarova D, Shibata S, Ishii I, Zlateva G, Zhelev Z, Aoki I, Higashi T, Bakalova RGen Physiol Biophys10.4149/gpb_2019001(2019/5) National Institutes for Quantum and Radiological Science and Technology (QST),
  Minimally invasive manganese-enhanced magnetic resonance imaging for the sciatic nerve tract tracing used intra-articularly administrated dextran–manganese encapsulated nanogels.Eguchi Y, Murayama S, Kanamoto H, Abe K, Miyagi M, Takahashi K, Ohtori S, Aoki I. JOR spine10.1002/jsp2.1059(2019/6/6) National Institutes for Quantum and Radiological Science and Technology (QST)
  Treatment of intervertebral disk disease by administration of messenger RNA encoding a cartilage-anabolic transcription factorC. -Y. Lin, S. T. Crowley, S. Uchida, Y. Komaki, K. Kataoka, K. ItakaMol. Ther. Nucleic Acids10.1016/j.omtn.2019.02.012(2019/6/7) China Medical University, Innovation Center of NanoMedicine, Tokyo Medical and Dental University (TMDU), The University of Tokyo, Central Institute for Experimental Animals, Policy Alternatives Research Institute
  Determination of cellular vitamin C dynamics by HPLC-DADTaiki Miyazawa, Akira Matsumoto, Yuji MiyaharaAnalyst10.1039/c8an02240b(2019/6/7) 東京医科歯科大学
  Anti- cancer effects of a chemically- modified mi R-143 on bladder cancer by either systemic or intravesical treatmentY. Yoshikawa, K. Taniguchi, T. Tsujino, K. Heishima, T. Inamoto, T. Takai, K. Minami, H. Azuma, K. Miyata, K. Hayashi, K. Kataoka, Y. AkaoMol. Ther. Methods. Clin.  Dev.10.1016/j.omtm.2019.02.005(2019/6/14) Gifu University, Osaka Medical College, The University of Tokyo, Inovation Center of NanoMedicine, Policy Alternatives Research Institute
  Translocation Mechanisms of Cell-Penetrating Polymers Identified by Induced Proton DynamicsTatsuro Goda, Yuki Imaizumi, Hiroaki Hatano, Akira Matsumoto, Kazuhiko Ishihara, Yuji Miyahara,
Langmuir10.1021/acs.langmuir.9b00856(2019/6/18)		 東京医科歯科大学、東京大学
  Label-free Nucleic Acid Amplification Detection using Electrochemical Sensors for Liquid BiopsyMiyuki Tabata, Yuji MiyaharaJournal of Photopolymer Science and Technology10.2494/photopolymer.32.97(2019/06/24) 東京医科歯科大学
  Dexamethasone increases cisplatin-loaded nanocarrier delivery and efficacy in metastatic breast cancer by normalizing the tumor microenvironmentJ. Martin, M. Panagi, C. Wang, T. Khan, M. Martin, C. Voutouri, K. Toh, P. Papageorgis, F. Mpekris, C. Polydorou, G. Ishii, S. Takahashi, N. Gotohda, T. Suzuki, M. Wilhelm, V. Melo, S. Quader, J. Norimatsu, R. Lanning, M. Kojima, M. Stuber, T. Stylianopoulos, K. Kataoka, H. CabralACS Nano10.1021/acsnano.8b07865(2019/6/25) The University of Tokyo, University of Cyprus, University of Connecticut, Innovation Center of NanoMedicine, European University Cyprus, National Cancer Center, National Cancer Center Hospital East, University of Connecticut, University of Colorado, Institute for Future Initiatives
  Design of a surface-functionalized power-free microchip for extracellular vesicle detection utilizing UV graftingRyo Ishihara, Asuka Katagiri, Tadaaki Nakajima, Ryo Matsui, Shuuhei Komatsu, Kazuo Hosokawa, Mizuo Maeda, Yasuhiro Tomooka, Akihiko KikuchiReactive and Functional Polymers10.1016/j.reactfunctpolym.2019.06.017(2019/6) 理化学研究所
  Serum MicroRNA-Based Risk Prediction for Stroke.Sonoda T, Matsuzaki J, Yamamoto Y, Sakurai T, Aoki Y, Takizawa S, Niida S, Ochiya T.Stroke.10.1161/STROKEAHA.118.023648(2019/6) 東京医科大学
  Fluorescent Polystyrene Latex Nanoparticles for NIR-II in vivo ImagingMasao Kamimura, Yuichi Ueya, Eiji Takamoto, Kazuhiro Iso, Moe Yoshida, Masakazu Umezawa, Kohei SogaJ PHOTOPOLYM SCI TEC10.2494/photopolymer.32.93(2019/6) 東京理科大学
  Photostabilization of Indocyanine Green Dye by Energy Transfer in Phospholipid-PEG MicellesGil Yeroslavsky, Masakazu Umezawa, Kyohei Okubo, Karina Nigoghossian, Doan Thi Kim Dung, Masao Kamimura, Kohei SogaJ PHOTOPOLYM SCI TEC10.2494/photopolymer.32.115(2019/6) 東京理科大学
  Smart Microneedle Fabricated with Silk Fibroin Combined Semi-Interpenetrating Network Hydrogel for Glucose-Responsive Insulin DeliveryChen Siyuan; Matsumoto Hiroko, Moro-oka Yuki, Tanaka Miyako, Miyahara Yuji, Suganami, Takayoshi, Matsumoto AkiraACS Biomaterials Science and Engineering10.1021/acsbiomaterials.9b00532(2019/7/1) 東京医科歯科大学、神奈川県産業技術総合研究所
  Abnormal axon guidance signals and reduced interhemispheric connection via anterior commissure in neonates of marmoset ASD model.Mimura K, Oga T, Sasaki T, Nakagaki K, Sato C, Sumida K, Hoshino K, Saito K, Miyawaki I, Suhara T, Aoki I, Minamimoto T, Ichinohe N.Neuroimage10.1016/j.neuroimage.2019.04.006(2019/7/15) National Institutes for Quantum and Radiological Science and Technology (QST)
  Bundling mRNA strands to prepare nano-assemblies with enhanced stability towards RNase for in vivo deliveryN. Yoshinaga, E. Cho, K. Koji, Y. Mochida, M. Naito, K. Osada, K. Kataoka, H. Cabral, S. UchidaAngew. Chem. Int. Ed.10.1002/anie.201905203(2019/8/12) The University of Tokyo, InnovationCenter of NanoMedicine (iCONM), NationalInstituteof Radiological Science, PolicyAlternatives ResearchInstitute
  Highly efficient silencing of microRNA by heteroduplex oligonucleotidesKotaro Yoshioka,Taiki Kunieda,Yutaro Asami, Huijia Guo ,Haruka Miyata,Kie Yoshida-Tanaka,Yumiko Sujino,Wenying Piao,Hiroya Kuwahara,Kazutaka Nishina,Rintaro Iwata Hara,Tetsuya Nagata,Takeshi Wada,Satoshi Obika,Takanori Yokota,Nucleic Acids Research10.1093/nar/gkz492(2019/8) 東京医科歯科大学
  Nanomaterial-Based Blood-Brain-Barrier (BBB) Crossing StrategiesJ. Xie, Z. Shen, Y. Anraku, K. Kataoka, X. ChenBiomaterials10.1016/j.biomaterials.2019.119491(2019/8) 東京大学、iCONM
  Enhancement of motor function 1 recovery after spinal cord injury in mice by delivery of brain derived neurotrophic factor mRNAS. T. Crowley, Y. Fukushima, S. Uchida, K. Kataoka, K. ItakaMol. Ther. Nucleic Acids10.1016/j.omtn.2019.06.016(2019/9/6) Tokyo Medical and Dental University (TMDU), Innovation Center of Nanomedicine (iCONM), Policy Alternatives Research Institute
  Cationic Copolymer‐Chaperoned 2D-3D Reversible Conversion of Lipid MembranesN. Shimada, H. Kinoshita, T. Umegae, S. Azumai, N. Kume, T. Ochiai, T. Takenaka, W. Sakamoto, T. Yamada, T. Furuta, T. Masuda, M. Sakurai, H. Higuchi, A. MaruyamaAdv. mater.10.1002/adma.201904032(2019/9) 東京工業大学
  Biological Deep Temperature Imaging with Fluorescence Lifetime of Rare-Earth-Doped Ceramics Particles in the Second NIR Biological WindowTakumi Chihara, Masakazu Umezawa, Keiji Miyata, Shota Sekiyama, Naoki Hosokawa, Kyohei Okubo, Masao Kamimura, Kohei SogaSCI REP-UK10.1038/s41598-019-49291-x(2019/9) 東京理科大学
  Cationic copolymer-chaperoned short-armed 10-23 DNAzymes NucleosidesO. Hanpanich, H. Miyaguchi, H. Huang, N. Shimada, A. MaruyamaNucleosides, Nucleotides & Nucleic Acids10.1080/15257770.2019.1675168 (2019/10/12) 東京工業大学
  Evaluation of the antitumor mechanism of antibody-drug conjugates against tissue factor in stroma-rich allograft models. Tsumura RCancer sci10.1111/cas.14146(2019/10) 国立がん研究センター
  All-polymer-based micro free-flow electrophoresis (μFFE) device with cellulose permeable membranesH. Takehara, S. Sato, T. IchikiApplied physics express10.7567/1882-0786/ab3d64(2019/10/1) University of Tokyo, Innovation Center of NanoMedicine
  Extracellular vesicles nanoarray technology: Immobilization of individual extracellular vesicles on nanopatterned polyethylene glycol-lipid conjugate brushesS. Yokota, H. Kuramochi, K. Okubo, A. Iwaya, S. Tsuchiya, T. IchikiPLOS ONE10.1371/journal.pone.0224091(2019/10/24) University of Tokyo, Innovation Center of NanoMedicine
  Radiation-induced redox alteration in the mouse brainNakamura M, Yamasaki T, Ueno M, Shibata S, Ozawa Y, Kamada T, Nakanishi I, Yamada KI, Aoki I, Matsumoto KI.Free Radic Biol Med10.1016/j.freeradbiomed.2019.08.020(2019/11/1) National Institutes for Quantum and Radiological Science and Technology (QST)
  Social Impact Bonds: Current Context and Implementation Model in the Healthcare IndustryDaitaro Misawa, Shintaro Sengoku2019 Portland International Conference on Management of Engineering and Technology (PICMET)10.23919/PICMET.2019.8893773(2019/11/7) Tokyo Institute of Technology
  Dually stabilized triblock copolymer micelles with hydrophilic shell and hydrophobic interlayer for systemic antisense oligonucleotide delivery to solid tumorBeob Soo Kim, Hyun Jin Kim, Shigehito Osawa, Kotaro Hayashi, Kazuko Toh, Mitsuru Naito, Hyun Su Min, Yu Yi, Ick Chan Kwon,  Kazunori Kataoka, Kanjiro MiyataACS Biomaterials Science & Engineering10.1021/acsbiomaterials.9b00384(2019/11/11) The University of Tokyo, Korea Institute of Science and Technology (KIST), Innovation Center of NanoMedicine, Tokyo University of Science, Policy Alternatives Research Institute
  Induced Proton Dynamics on Semiconductor Surfaces for Sensing Tight Junction Formation Enhanced by an Extracellular Matrix and DrugHiroaki Hatano, Tatsuro Goda, Akira Matsumoto, Yuji MiyaharaACS Sensors10.1021/acssensors.9b01635(2019/11/25) 東京医科歯科大学
  Single-stranded DNA-packaged polyplex micelle as adeno-associated-virus-inspired compact vector to systemically target stroma-rich pancreatic cancerT. A. Tockary, W. Foo, A. Dirisala, Q. Chen, S. Uchida, S. Osawa, Y. Mochida, X. Liu, H. Kinoh, H. Cabral, K. Osada, K. KataokaACS Nano10.1021/acsnano.9b04676(2019/11/26) Innovation Center of NanoMedicine (iCONM), The University of Tokyo, Dalian University of Technology, Tokyo University of Science, National Institutes for Quantum and Radiology Science and Technology, Institute for Future Initiatives
  Fine-tuning of hydrophobicity in amphiphilic polyaspartamide derivatives for rapid and transient expression of messenger RNA directed toward genome engineering in brainHyun Jin Kim, Satomi Ogura, Takahiro Otabe, Rimpei Kamegawa, Moritoshi Sato, Kazunori Kataoka, Kanjiro MiyataACS Central Science10.1021/acscentsci.9b00843(2019/11/27) 東京大学
  Sensitivity enhancement of microRNA detection using a power-free microfluidic chipYoung-Jin Kim, Kazuo Hosokawa, Mizuo MaedaAnalytical Sciences10.2116/analsci.19P211(2019/11) 理化学研究所
  U3-1402, a Novel HER3-Targeting Antibody-Drug Conjugate, for the Treatment of Colorectal Cancer. Koganemaru SMol Cancer Ther.10.1158/1535-7163(2019/11) 国立がん研究センター
  Cationic Copolymers Act As Chaperones of a Membrane-Active Peptide: Influence on Membrane SelectivityW. Sakamoto, T. Masuda, T. Ochiai, N. Shimada, A. MaruyamaACS Biomaterials Science & Engineering10.1021/acsbiomaterials.8b01582(2019/11) 東京工業大学
  Topological analysis of TMEM180, a newly identified membrane protein that is highly expressed in colorectal cancer cells. Anzai TBiochem Biophys Res Commun. 10.1016/j.bbrc.2019.10.070(2019/12) 国立がん研究センター
  Cytoplasmic fusion between an enlarged embryonic stem cell and a somatic cell using a microtunnel deviceSeong Min Kim, Ken-Ichi Wada, Masashi Ueki, Kazuo Hosokawa, Mizuo Maeda, Yasuyuki Sakai, Yoshihiro ItoBiochemical and Biophysical Research Communications10.1016/j.bbrc.2019.09.131(2019/12) 理化学研究所
  Assessment of the Diagnostic Utility of Serum MicroRNA Classification in Patients
With Diffuse Glioma.Ohno M, Matsuzaki J, Kawauchi J, Aoki Y, Miura J, Takizawa S, Kato K, Sakamoto
H, Matsushita Y, Takahashi M, Miyakita Y, Ichimura K, Narita Y, Ochiya T.JAMA Netw Open.10.1001/jamanetworkopen.2019.16953(2019/12)		 東京医科大学
  Serum microRNA profile
enables preoperative diagnosis of uterine leiomyosarcoma.Yokoi A, Matsuzaki J, Yamamoto Y, Tate K, Yoneoka Y, Shimizu H, Uehara T, Ishikawa M, Takizawa S, Aoki Y, Kato K, Kato T, Ochiya T.Cancer Sci.10.1111/cas.14215(2019/12)		 東京医科大学
  Near-infrared Biomedical Imaging for TransparencyKohei SOGA, Masao KAMIMURA, Kyohei OKUBO, Masakazu UMEZAWA, Thi Kim Dung DOAN, Karina NIGOGHOSSIANJournal of the Imaging Society of Japan10.11370/isj.58.602(2019/12) 東京理科大学
  Adsorption phenomena of anionic and cationic nanoliposomes on the surface of poly(dimethylsiloxane) microchannelV. Majarikar, H. Takehara, T. IchikiJournal of Photopolymer Science and Technology10.2494/photopolymer.32.107(2019/12/18) University of Tokyo, Innovation Center of NanoMedicine
  TGF-β inhibition combined with cytotoxic nanomedicine normalizes triple negative breast cancer microenvironment towards anti-tumor immunityM. Panagi, C. Voutouri, F. Mpekris, P. Papageorgis, M. R. Martin, J. D. Martin, P. Demetriou, C. Pierides, C. Polydorou, A. Stylianou, M. Louca, L. Koumas, P. Costeas, K. Kataoka, H. Cabral, T. StylianopoulosTheranostics10.7150/thno.36936(2020/1/12) University of Cyprus, European University Cyprus, The University of Tokyo, The Center for the Study of Haematological Malignancies, Karaiskakio Foundation, Innovation Center of NanoMedicine, Policy Alternatives Research Institute
  Polymeric micelles loading proteins through concurrent ion complexation and pH-cleavable covalent bonding for in vivo deliveryA. Tao, G. L. Huang, K. Igarashi, T. Hong, S. Liao, F. Stellacci, Y. Matsumoto, T. Yamasoba, K. Kataoka, H. CabralMacromol. Biosci.10.1002/mabi.201900161(2020/1/17) The University of Tokyo, Ecole Polytechnique Federale de Lausanne, Innovation Center of NanoMedicine (iCONM), Institute for Future Initiatives
  Highly efficient gene silencing in mouse brain by overhanging-duplex oligonucleotides via intraventricular route.Su Su Lei Mon, Kotaro Yoshioka, Chunyan Jia, Taiki Kunieda, Yutaro Asami, Kie-Yoshida-Tanaka, Wenying Piao, Hiroya Kuwahara, Kazutaka Nishina, Tetsuya Nagata, Takanori YokotaFEBS　Letters10.1002/1873-3468.13742(2020/1) 東京医科歯科大学
  Nascent SecM chain interacts with outer ribosomal surface to stabilize translation arrestMikihisa Muta, Ryo Iizuka, Tatsuya Niwa, Yuanfang Guo, Hideki Taguchi, Takashi FunatsuBiochemical Journal10.1042/BCJ20190723(2020/1) 東京大学
  Poly(vinyl alcohol) boosting therapeutic potential of p-boronophenylalanine in neutron capture therapy by modulating metabolism. T. Nomoto, Y. Inoue, Y. Yao, M. Suzuki, K. Kanamori, H. Takemoto, M. Matsui, K. Tomoda, N. NishiyamaScience Advances10.1126/sciadv.aaz1722(2020/1) 東京工業大学、iCONM
  New potential biomarker for stratification of patients for pharmacological vitamin C in adjuvant settings of cancer therapyBakalova R, Zhelev Z, Miller T, Aoki I, Higashi T.Redox Biology10.1016/j.redox.2019.101357(2020/1) National Institutes for Quantum and Radiological Science and Technology (QST),
  Development of an Automated Sample Injection System for Pillar Array ColumnsHiroshi Kuroki, Hirotaka Koyama, Yusuke Nakatani, Takashi Funatsu, Shigeyoshi Horiike, Makoto TsunodaChromatography10.15583/jpchrom.2019.022(2020/2/20) 東京大学、株式会社島津製作所
  A 50 nm-sized micellar assembly of thermoresponsive polymer-antisense oligonucleotide conjugates for enhanced gene knockdown in lung cancer by intratracheal administrationBeob Soo Kim, Shigehito Osawa, Mitsuru Naito, Satomi Ogura, Rimpei Kamegawa, Hiroki Ishida, Hyun Jin Kim, Satoshi Uchida, Kanjiro MiyataAdvanced Therapeutics10.1002/adtp.201900123(2020/2) 東京大学、iCONM
  Polymeric modification of gemcitabine via cyclic acetal linkage for enhanced anticancer potency with negligible side effects. H. Takemoto, T. Inaba, T. Nomoto, M. Matsui, X. Liu, M. Toyoda, Y. Honda, K. Taniwaki, N. Yamada, J. Kim, K. Tomoda, N. NishiyamaBiomaterials10.1016/j.biomaterials.2020.119804(2020/3) 東京工業大学、iCONM

その他(総説・図書）

No. タイトル・発表者等 発表機関
  3次元細胞凝集塊の非侵襲的な回収および細胞機能向上を目的とした細胞培養技術開発位髙啓史三次元培養における培養手法と周辺技術動向(2019/4/17) 東京医科歯科大学
  脳神経疾患におけるmRNA医薬の応用を目指した技術開発位髙啓史認知症の早期診断技術と進行抑制/予防薬・機能性食品の開発(2019/4/26) 東京医科歯科大学
  mRNA医薬開発の世界的動向位髙啓史、秋永士朗、井上貴雄医薬品医療機器レギュラトリーサイエンス(2019/4) 東京医科歯科大学、アキュルナ株式会社
  Design concepts of polyplex micelles for in vivo therapeutic delivery of plasmid DNA and messenger RNAS. Uchida, K. KataokaJ. Biomed. Mater. Res. A10.1002/jbm.a.36614(2019/5/1) The University of Tokyo, Innovation Center of NanoMedicine (iCONM), Policy Alternatives Research Institute
  「ボロノレクチン」工学が拓く新しい治療オプション松元亮、菅波孝祥、宮原裕二MDB技術予測レポート‐2050年　未来・世界を変える技術‐, 株式会社日本能率協会総合研究所マーケティング・データ・バンク（MDB）(2019/5/1) 東京医科歯科大学、名古屋大学
  “エレクトロニクスフリー”で完全合成型の人口膵臓の開発松元亮バイオサイエンスとインダストリー, B&I (2019/5/10) 東京医科歯科大学
  核酸医薬のDDSに関する開発動向内藤瑞、宮田完二郎医薬品モダリティの特許戦略と技術開発動向(2019/5) 東京大学
  ナノ・マイクロ構造体を利用した蛍光イメージング飯塚怜化学工業(2019/5) 東京大学
  血液脳関門を標的とした核酸医薬による分子標的治療の開発桑原宏哉、横田隆徳技術情報協会・医薬品モダリティの特許戦略と技術開発動向(2019/5) 東京医科歯科大学
  Involvement of Extracellular  Vesicles in Vascular-Related Functions in Cancer Progression and MetastasisKikuchi S, Yoshioka Y, Prieto-Vila M, Ochiya T.Int J Mol Sci.10.3390/ijms20102584(2019/5) 東京医科大学
  核酸医薬のためのDDS西山伸宏医学のあゆみ(2019/5) 東京工業大学、iCONM
  mRNA医薬品の品質・安全性評価の考え方荒戸照世、位髙啓史、秋永士朗、佐藤秀昭、山口照英、真木一茂、内田恵理子、吉田徳幸、井上貴雄医薬品医療機器レギュラトリーサイエンス(2019/6/1) 東京医科歯科大学
  ボロノレクチンを利用したバイオエンジニアリング松元亮、宮原裕二医学のあゆみ, 医歯薬出版株式会社(2019/6/1) 東京医科歯科大学
  Chemistry enabling “magic bullet”K. KataokaL'Act. Chim.(2019/7/3) Institute for Future Initiatives, The University of Tokyo, Innovation Center of NanoMedicine (iCONM)
  Nanomedicines for reactive oxygen species mediated approach: An emerging paradigm for cancer treatmentS. -L. Kwon, H. -W. Ko, D. -G. You, K. Kataoka, J. -H. ParkAcc. Chem. Res.10.1021/acs.accounts.9b00136(2019/7/16) Innovation Center of NanoMedicine, Institute for Future Initiatives
  Ligand-installed nanocarriers towards precision therapyP. Mi, H. Cabral, K. KataokaAdv. Mater.doi.org/10.1002/adma.201902604(2019/7/28) The University of Tokyo, Innovation Center of Nanomedicine (iCONM), Institute for Future Initiatives
  ブロック共重合体で見る一分子pDNA複合体が造る高次構造とその制御長田健介ナノファイバー(2019/7/31) 量子科学技術研究開発機構
  生体吸収性マイクロニードルの精密成形加工と材料強度評価竹原宏明、一木隆範PHARM STAGE 7月号(2019/7) 東京大学
  Consortium-Based Open Innovation:
Exploring a Unique and Optimal Model
for Regional Biotechnology IndustryShintaro SengokuInnovation beyond technology10.1007/978-981-13-9053-1_7(2019/8/1)		 東京工業大学
  Determination of intra- and extra-cellular vitamin C dynamics; the simplest-ever and label-free chromatographic techniqueTaiki Miyazawa, Akira Matsumoto*, Yuji MiyaharaGIT. Laboratory J(2019/9/7) 東京医科歯科大学
  Liquid Biopsy in Combination with Solid-state Electrochemical Sensors and Nucleic Acid AmplificationMiyuki Tabata, Yuji MiyaharaJournal of Materials Chemistry B10.1039/C9TB00718K(2019/9/1) 東京医科歯科大学
  副作用を減らす② 抗がん剤をナノカプセルでがん細胞に届ける片岡一則ニュートン別冊　くすりの科学知識 増補第2版 薬のしくみと、奥深き創薬の世界(2019/11/5) iCONM
  Smart oligonucleotide delivery by multifunctional block copolymersKotaro Hayashi, Kanjiro MiyataMaterial Matters(2019/11/1) iCONM、東京大学
  血中グルコース濃度の変化に応答した効率的な血液脳関門通過型DDS桑原宏哉、横田隆徳Drug Delivery System(2019/11/1) 東京医科歯科大学
  Biomaterials Science and Engineering in Japan: Attractive, Multidisciplinary, and Essential Research Field in JapanAkira Matsumoto, Keiji NumataACS Biomaterials Science and Engineering10.1021/acsbiomaterials.9b01613(2019/11/1) 東京医科歯科大学、理化学研究所
  Nanomaterial-based blood-brain-barrier (BBB) crossing strategiesJ. Xie, Z. Shen, Y. Anraku, K. Kataoka, X. ChenBiomaterials10.1002/adma.201902604(2019/12/21) Innovation Center of NanoMedicine, Policy Alternatives Research Institute
  人工膵臓デバイスによる血糖管理の未来木村真一郎、田中都、松元亮、菅波孝祥Pharma Medica(2019/12/1) 東京医科歯科大学、名古屋大学
  mRNA医薬に利用されるキャリア開発：ナノミセル型キャリア位髙啓史Drug Delivery System(2020/1/25) 東京医科歯科大学
  Cancer Drug Delivery Systems Based on the Tumor MicroenvironmentMatsumura Y Tarin D編集Springer(2020/1) 国立がん研究センター

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