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Registration has been opened now!
【Information】We will hold the COINS Seminar #50 at iCONM.
December 6 (Fri.) 11:00-12:00 *There is no research mixer.
Speaker: Prof. Kris Matyjaszewski/J.C. Warner University Professor of Natural Sciences, Carnegie Mellon University
Title: Bio-related ATRP
Venue: Innovation Center of NanoMedicine (iCONM) 3F 3001 Access
Click here for details

【Reservation is required】Registration
Registration has been opened now!
【Information】We will hold the 6th COINS Symposium.
Date: Dec 13 (Fri.) 13:00~(Registration open at 12:30)
Venue: Kawasaki City Industrial Promotion Hall Access
language: English - Japanese *Simultaneous interpretation is provided.

【Register now】Registration and program is here.
Now open
【Information】At At The National Museum of Emerging Science and Innovation known as "Miraikan" (Aomi, Koto-ku, Tokyo), an opinion bank about the "In-body hospitals" that iCONM draws for the future is now oepn to the public. We look forward to your feedback, as we will gather the voices of visitors to the museum and use them for future research.
11.11.2019
【Articles Published】Professor Kazunori Kataoka, Research Leader of COINS, was published in The Chemical Daily on 11.11.2019
11.8.2019
【Articles Published】The article about Dr. Ichiki Takanori (Professor, The University of Tokyo), who is a leader of COINS Theme 4 was appeared in The Nikkei Business Daily on 11.08.2019
  • Analysis of exosomes one by one | Nikkei Business Daily
11.7.2019
【Press release】iCONM and Braizon Therapeutics will hold a luncheon meeting at The 41st Annual Meeting of The Japanese Society for Biomaterials on 25 Nov.
Click here for details (Japanese)
11.2.2019
【Activity Report】Nov 2th (Sat.), a public talk was held at Miraikan(The National Museum of Emerging Science and Innovation)
Click here for details (Japanese)
10.28.2019
【Articles Published】COINS reseacher Dr. Sabina Quader, was published in The Chemical Daily on 10.28.2019
10.25.2019
【Published Articles】Announcement of the 6th COINS Symposium was published in Kanagawa Shimbun.
  • Introduction of advanced medical research: COINS Symposium on December 13
10.25.2019
【Press conference】We held a press conference by Prof. Kazunori Kataoka (Director General of iCONM), Dr. Kensuke Osada (Senior Scientist of QST) and Dr. Theofilus A. Tockary (Research Scientist of iCONM) . A novel technology has been developed to convert the double helix structure of DNA into a single strand of DNA (ssDNA), roll it into a compact form, and encapsulate it inside a smart nanomachine.
Click here for details

This research result was published in "ACS Nano"
The article was introduced on the newspapers.
  • iCONM-National Institutes for Quantum and Radiological Science and Technology, pancreatic cancer growth inhibition, synthetic vector development | Chemical Daily
  • Deliver single-stranded DNA to pancreatic cancer using high molecular weight vectors such as iCONM | Nikkei Biotech ONLINE
  • World's first suicide gene therapy for pancreatic cancer| Nikkei BeyondHealth
10.24.2019
【Press release】The University of Tokyo made a press release that the paper titled "develop the world's first exosome array chip that enables single nanoparticle measurement" by Dr. Takanori Ichiki, professor of The University of Tokyo (COINS theme 4 leader) and his team was posted on line on October 24 (EST).
10.24.2019
【Activity Report】Oct 24th (Thu.), COINS Seminar #49 was held at iCONM.
Speaker: Prof. Dr. Rainer Haag
Chair Professor of Organic and Macromolecular Chemistry, Department of Chemistry and Biochemistry, Freie Universität Berlin, Germany.
Title: “Multivalent Nanosystems and Supramolecular Dendritic Architectures”
Click here for details
10.21.2019
【Report】An interview with Hiromichi Kimura(Project Leader of COINS) was published in The Chemical Daily on 10.21.2019
10.18.2019
【Activity Report】“COINS Retreat Camp 2019” was held on 18th~19th October.
Click here for details
10.16.2019
【Press release】An interview with Deputy Director Iwasaki was broadcasted on BS TV Tokyo “Nikkei Plus 10” on Wednesday, October 16.
In the special feature “2020 Changing Tokyo (1) Towards tourism country・Increaing Haneda International Flights has the Key”, he was interviewed what kind of changes would happen at King Skyfront when the Haneda connecting road opens. The broadcast contents is viewed on the program distribution service.
10.16.2019
【News coverage】An article of COINS venture companies Braizon Therapeutics, Inc. was published in Chemical Daily. (October 16, 2019)
  • Braizon develops childhood brain tumor drugs in-house, applying DDS to known anticancer drugs | Chemical Daily
10.10.2019
【Press release】The article about Dr. Yasutaka Anraku (Project Professor, The University of Tokyo), who is a leader of COINS Theme 2 was appeared in JSTnews.
9.19.2019
【Information】We will hold the COINS Seminar #49 at iCONM.
October 24 (Thu.) 16:00-17:15/Research Mixer 17:15-18:15 *JPY500
Speaker: Prof. Dr. Rainer Haag/Chair Professor of Organic and Macromolecular Chemistry, Department of Chemistry and Biochemistry, Freie Universität Berlin, Germany
Title: Multivalent Nanosystems and Supramolecular Dendritic Architectures
Venue: Innovation Center of NanoMedicine (iCONM) 3F 3001 Access
Click here for details
*Registration is now closed.
9.15.2019
【Report】Articles about Prof. Ken Masamune (Professor, Tokyo Women's Medical University)who is a member of our center's COINS project,Published in the magazine Pharmaceutical Economics.
  • Integrate information to predict postoperative. Practitioner of medical-industrial collaboration 6 Ken Masamune, Professor, Tokyo Women's Medical University.
9.13.2019
【Report】An interview with Dr.Shiro Akinaga, President of AccuRna, Inc., the main project COINS, was published in the Nikkei Business Daily.
  • Dr.Shiro Akinaga, President of AccuRna, Inc.,-Nucleic acid medicine in clinical settings | Nikkei Business Daily
9.11.2019
【Award】Akira Matsumoto, Associate Professor (Tokyo Medical and Dental University),received 68th SPSJ Annual Meeting of the Publicity Award.
  • Title:Microneedle type "just stick" artificial pancreas: dramatically improved invasiveness, stability, economy and aesthetics
9.5.2019
【Activity Report】Sep 5th (Thu.), COINS Seminar #48 was held at iCONM.
Speaker: Dr. Hiroaki Taniguchi
Project Associate Professor, Keio Cancer Center & Clinical and Translational Research Center, Keio University School of Medicine..
Title: " PRDM14 silencing by siRNA combined with an innovative nanoparticle reduced tumor formation and metastasis "
Click here for details
8.28.2019
【Activity Report】Aug 28th (Wed.), COINS Seminar #47 was held at iCONM.
Part1
Speaker: Hiroo Iwata
Dr. Eng. / Manager, Strategy Research Support Section of Center of Innovation Program, Kyoto U.
Title: " Cell Lego "
Part2
Speaker: Peilin Chen
Professor / Research Fellow, Research Center for Applied Sciences, Academia Sinica, Taiwan.
Title: " Isolation of Rare Cells: Toward Noninvasive Diagnostic "
Click here for details
8.21.2019
【Activity Report】Takuya HIRAI(Minister in charge of Information Technology Policy, "Cool Japan" Strategy, the Intellectual Property Strategy, Science and Technology Policy, Space Policy)visited King Skyfront.
8.20.2019
【Press release】AccuRna Inc. announced that the company enters into a Feasibility Study Agreement with Astellas Innovation Management LLC subsidiary of Astellas Pharma Inc for the use of delivery system of polymer micelle1 loaded with messenger RNA (mRNA) under pre-clinical development by AccuRna.
Press release text
8.19-22.2019
【Award】Dr. Junjie Li, a JSPS Postdoctoral Fellow for Research in Japan received CASNN Best Poster Award at Chinese-American Society of Nanomedicine and Nanobiotechnology 2019 Annual Conference held on August 19 – 22 in Hangzhou, China. He proposed the method that accurately distinguishes cancer tissue from normal tissue and attacks only cancer tissue with high accuracy by the experiments with multifunctional nanocarriers.
Related page is here.
8.15.2019
【Report】Articles about Prof. Kouhei Soga (Professor, Tokyo University of Science)who is a member of our center's COINS project,Published in the magazine Pharmaceutical Economics.
  • In-vivo imaging with near-infrared. Practitioner of medical-industrial collaboration 4 Kouhei Soga, Professor, Tokyo University of Science.
8.9.2019
【Information】We will hold the COINS Seminar #48 at iCONM.
September 5 (Thu.) 16:00-17:15/Research Mixer 17:15~18:15 *JPY500
Speaker: Hiroaki Taniguchi/Project Associate Professor, Keio Cancer Center & Clinical and Translational Research Center, Keio University School of Medicine.
Title: PRDM14 silencing by siRNA combined with an innovative nanoparticle reduced tumor formation and metastasis

Venue: Innovation Center of NanoMedicine (iCONM) 3F 3001 Access
Click here for details
*Registration is now closed.
8.8.2019
【Information】We will hold the COINS Seminar #47 at iCONM.
August 28 (Wed.) 15:00-16:30 *There is no research mixer.
◆Part.1
Speaker: Hiroo Iwata / Manager, Strategy Research Support Section of Center of Innovation Program, Kyoto U.
Title: Cell Lego
◆Part.2
Speaker: Peilin Chen / Research Fellow, Research Center for Applied Sciences, Academia Sinica, Taiwan.
Title: Isolation of Rare Cells: Toward Noninvasive Diagnostic

Venue: Innovation Center of NanoMedicine (iCONM) 3F 3001 Access
Click here for details
*Registration is now closed.
8.8.2019
【Report】COINS' venture company Braizon Therapeutics, Inc. was selected as one of the ten startups as the recipients of support measures under the first round of a call for applicants for the FY2019 IP. They will be able to receive support of an “IP Mentoring Team” consisting of selected experts in the fields of business and IP for help to develop IP strategies for accelerating their businesses.
8.8.2019
【Report】Interviews with COINS venture companies Blazon Therapeutics, Inc. and President Mariko Tosu were published in Nikkei Beyond Health. It describes the company's technology, which was established through the social implementation of nanomachines that can cross the blood-brain barrier, and the future prospects.
8.6.2019
【Press release】An article commented by Prof. Yasuhiro Matsumura (National Cancer Research Center) who is a member of our center's COINS Project was published in Nikkei Business Daily Electronic Edition and Nikkei Business Daily(date of August 6, 2019).
  • Discovering the phenomenon of drugs gathering in cancer, maintaining the effectiveness of anticancer drugs (trajectory of innovation)
8.5.2019
【Press release】The article about Dr. Keiji Itaka (Professor, Tokyo Medical and Dental University), who is a leader of COINS Theme 3 was appeared in Daily pharmaceutical industry.
  • "mRNA medicine" breaks or attention strain following nucleic acid medicine
8.5.2019
【Report】An article commented by Prof. Yasuhiro Matsumura (National Cancer Research Center) who is a member of our center's COINS Project was published in Nihon Keizai Shimbun Electronic Edition and Nihon Keizai Shimbun (date of August 5, 2019).
  • Aiming for cells and tissues that interfere with the efficacy of “cancer allies”
7.31.2019
【Report】Articles about Prof. Takahiro Ochiya (Professor, Tokyo Medical University, Visiting Researcher, National Cancer Center Research Institute)who is a member of our center's COINS project. Published in Nihon Keizai Shimbun Electronic Edition and Nihon Keizai Shimbun (date of July 31, 2019) .
  • Early cancer test in blood, "garbage" breaks through (report), can cancer be overcome (3)
7.31.2019
【Activity Report】July 31 (Wed.), COINS Seminar #46 was held at iCONM.
Speaker: Dr. Nuno M. Neves
Associate Professor, University of Minho / Vice Director of 3B’s.
Title: "Nanoparticles and Nanofibrous Scaffolds Combined with Stem Cells for Advanced Therapies"
Click here for details
7.31.2019
【Information】We will hold the COINS Seminar #46 at iCONM.
July 31 (Wed.) 16:00-17:00 *There is no research mixer.
Speaker: Nuno M. Neves
Associate Professor, University of Minho /Vice Director of 3B's.
Title: Nanoparticles and Nanofibrous Scaffolds Combined with Stem Cells for Advanced Therapies
Venue: Innovation Center of NanoMedicine (iCONM) 3F 3001 Access
Click here for details
*Registration is now closed.
7.26-27.2019
【Report】An article about Prof. Yasuhiro Matsumura (National Cancer Research Center), member of our center's COINS project, was published in the evening paper Fuji.
  • 26th:A new treatment "DDS" that strikes cancer cells and breaks through barriers
  • 27th:Interstitial Targeting Therapy to Challenge High-grade Cancer
7.15-17.2019
【Activity Report】<Prof. Kataoka gave a keynote speech at "Symposium on Innovative Polymers for the Nanomedicine of the 21st Century">
At "Symposium on Innovative Polymers for the Nanomedicine of the 21st Century" held at Jena in Germany on July 15-17, Prof. Kazunori Kataoka gave a keynote speech entitled as "Self-assembled supramolecular nanosystems for smart diagnosis and targeted therapy of intractable diseases". Around 140 experts in the field of nanomedicine met at the Symposium and the current state of research was recapitulated and new perspectives were actively discussed.
Related page is here.
7.15.2019
【Report】The article about the research team of Dr. Keiji Itaka (Professor, Tokyo Medical and Dental University), who is a leader of COINS Theme 3 was appeared in Nikkei Shimbun Electronic version and Nihon Keizai Shimbun morning page 10 (date of July 15, 2019).
  • Recovery by spinal cord injury mouse RNA administration
7.15.2019
【Report】The article about the research which has beem carrying out at COINS in iCONM was appeared in Nikkei Shimbun Electronic version and Nihon Keizai Shimbun morning page 10 (date of July 15, 2019).
  • Brain gene therapy, clinical trials progress Alzheimer's and ALS overseas leader, Japan is mass production issue
7.15.2019
【Report】An interview article by Kataoka (Director General of iCONM, Professor, The University of Tokyo) has been published in the magazine Pharmaceutical Economics. It describes the background that Dr. Kataoka has spent and the elements that are necessary for a successful medical-industrial collaboration.
  • From DDS to "In Body Hospitals" Practitioner of medical-industrial collaboration 2 Kazunori Kataoka Director, Center for Nanomedical Innovation.
7.8.2019
【Press release】The article about the research team of Dr. Keiji Itaka (Professor, Tokyo Medical and Dental University), who is a leader of COINS Theme 3 was appeared in Qlife Pro.
7.4.2019
【Press release】Tokyo Medical and Dental Universiy has made a press release that a manuscript "Enhancement of Motor Function Recovery After Spinal Cord Injury in Mice by Delivery of Brain Derived Neurotrophic Factor mRNA" by Dr. Keiji Itaka, COINS theme 3 leader, Professor, Tokyo Medial and Dental University, et al. has been published online in "Molecular Therapy-Nucleic Acids" on June 28, 2019.
Press release text
6.28.2019
【Press release】"Nanomachines that carry nucleic acid medicine for fundamental treatment of hereditary intractable disease. Launched crowdfunding for R&D and disease enlightenment."
・Start research and development of nucleic acid medicines that lead to fundamental treatment of designated intractable disease "cystic fibrosis".
・Start recruitment of crowdfunding in partnership with Academia Mist.
・The recruitment period is between June 28-August 26. The target amount is ¥ 400,000.
・Expect to connect not only to raising research funding but also to social enlightenment of “cystic fibrosis”.
Press release text

Cystic fibrosis is a rare disease that occurs at a rate of 1 in 600,000 people in Japan, and highly viscous secretions are excessively secreted in major organs throughout the body, such as the lungs and the pancreas. It is a disease that causes various pains such as dyspnea and digestive disorders.
Currently, there is no drug effective for the fundamental treatment, and it is classified as a designated intractable disease by the Ministry of Health, Labor and Welfare.
Your support is very much appreciated.
Please click here for details.
6.25.2019
【Activity Report】June 25th (Tue.), COINS Seminar #45 was held at iCONM.
Speaker: Dr. Makoto Miyagishi
Group Leader, Molecular Composite Medicine Research Group,
Biomedical Research Institute, Advanced Industrial Science and Technology (AIST)
Title: " Development of screening method of nucleic acid aptamer, and its application to finding of DNA/RNA catalyst"
Click here for details
6.24.2019
【Report】Announcing a new choice of startup support program "J-Startup" by public and private!
The Ministry of Economy, Trade and Industry has newly identified 49 companies as startup support companies and announced their press.
COINS's venture company Brazon Therapeutics is among the 49 companies.
About the selection of "J-Startup 2019" | Ministry of Economy, Trade and Industry
6.14.2019
【Activity Report】12th COINS General meeting was held on 14th June.
Related page is here.
6.5.2019
【News Coverage】Research Leader, Kazunori Kataoka (Director General of
iCONM, Professor, The University of Tokyo) gave a talk at Link-J Networking Reception UCLA Health : Partnering with Industry to Advance Healthcare that held on 5/16. He talked about the academic exchange with UCLA that lasts for more than a decade.
6.3.2019
【Report】AccuRna, Inc. one of the participating institutions announced that they will start
clinical trials for breast cancer treatment with SiRNA based nucleic acid medicines later this year.
  • AccuRna starts triple negative breast cancer (TNBC) treatment with nucleic acid medicines. | The Chemical Daily
5.31.2019
【Award】 Takuya Nishizono (The University of Tokyo) received the Polymer Society of Japan Excellent Poster Award at the 68th SPSJ Annual Meeting Best poster award.
  • Title:Evaluation on brain accumulation and distribution of nanocarriers with different sizes
5.31.2019
【Award】 Yoshihiro Tachihara (The University of Tokyo) received the Polymer Society of Japan Excellent Poster Award at the 68th SPSJ Annual Meeting Best poster award.
  • Title:Development of pH-Sensitive Polymeric Micelles for Targeted Delivery of the Macrocycle Valinomycin via Host Guest Interaction
5.30.2019
【Information】Professor Kazunori Kataoka, Research Leader of COINS, was installed as an Honorary Member of the Society of Polymer Science, Japan.
5.24.2019
【Information】We will hold the COINS Seminar #45 at iCONM.
June 25th (Tue.) 16:00–17:15 (Research Mixer 17:15~18:15 *JPY500)

Speaker: Dr. Makoto Miyagishi
Group Leader, Molecular Composite Medicine Research Group, Biomedical Research Institute, Advanced Industrial Science and Technology (AIST).

Title: Development of screening method of nucleic acid aptamer, and its application to finding of DNA/RNA catalyst

Venue: Innovation Center of NanoMedicine (iCONM) 3F 3001 Access

Click here for details
*Registration is now closed.
5.14.2019
【Activity Report】May 14th (Tue.), COINS Seminar #44 was held at iCONM.
Speaker: Dr. Hiroyuki Fujita
Professor, Tokyo City University, Advanced Research Lab.
Title: "MEMS Technology and Applications to Biomedical Field"
Click here for details
4.26.2019
【TV】Research Leader, Kazunori Kataoka (Director General of iCONM, Professor, The University of Tokyo) is going to appear on TV program!
  • 29 April 8:00-10:30 AM Nippon Televison 『Sukkiri』
4.26.2019
【TV】Research Promotion Leader of COINS, Mr. Hirokazu Iwasaki is going to appear on TV program tomorrow!
  • 26 April 6:00PM TVK 『NEWS Harbor』
4.23.2019
【Press Release】We held a press conference by Kazunori KATAOKA(Director General, iCONM / Professor, The of Tokyo)and Kanjiro MIYATA, COINS Theme 1 leader(Associate Professor, The University of Tokyo / Visiting Scientist, iCONM). They succeeded in developing the Nucleic Acid Medicine-loaded Nanomachine, a technology that can stably protect nucleic acid drugs that are prone to deactivation in the bloodstream and deliver them to intractable cancers such as pancreatic cancer and brain tumors.
Click here for details.

This research result was published in "Nature Communications (UK scientific journal)" on Wednessday, April 24, 2019.

The articles regarding this matter were introduced on some newspapers.
Click here for more details of the press conference.
The list of media coverage
4.16.2019
【Activity Report】COINS Seminar #43 was held at Kawasaki King Skyfront Tokyu REI Hotel.
Part1
Speaker: Mr. Kazuomi Iwatani
Manager, Intellectual Property Division
Japan Agency for Medical Research and Development(AMED)
Title: "The briefing session of support program by Intellectual Property Division of AMED"

Part2
Speaker: Dr. Hiroatsu Nohara
Associated Researcher, Affiliation: Lest-CNRS / Aix-Marseille University
Title: "French medical cluster: the case of “Oncopole” in Toulouse"
Click here for details
4.14.2019
【Information】We will hold the COINS Seminar #44 at iCONM.
May 14th (Tue.) 16:00–17:15 (Research Mixer 17:15-18:15 *JPY500)
Speaker: Dr. Hiroyuki Fujita
Professor, Tokyo City University, Advanced Research Lab.
Title: MEMS Technology and Applications to Biomedical Field

Venue: Venue: Innovation Center of NanoMedicine (iCONM) 3F 3001 Access
Click here for details
*Registration is now closed.
4.9.2019
【Award】Dr. Nobuhiro Nishiyama, Leader of Theme 5 (Professor, Institute of Innovative Research, Tokyo Institute of Technology / Principal Research Scientist / Laboratory Head, KAWASAKI INSTITUTE OF INDUSTRIAL PROMOTION Innovation Center of NanoMedicine(iCONM)) was awarded The Prize for Science and Technology (Research Category) for The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology.
His research title was “Study on development and medical application of nanomachines based on polymer design".
4.3.2019
【Information】COINS SDGs promotion video has been completed. This is request from JST.
We are proactively contributing to the achievement of the SDGs goal 3 of "Good health and well-being". We hope you enjoy it!
4.1.2019
【News Coverage】Research Leader, Kazunori Kataoka (Director General of iCONM, Professor, The University of Tokyo) interview was introduced on THEMIS magazine (1 April).
  • Dr. Kazunori Kataoka, Director-General, Innovation Center of NanoMedicine faces the challenge to eliminate cancer and Alzheimer's disease with polymer micelle

About COINS

COINS (Center of Open Innovation Network for Smart Health) is a research center of an entirely new idea for developing "products and services that changes the future" by anticipating social needs in the future and integrating cutting-edge technologies, human resources and ideas from universities and private companies in and outside Japan.

COINS is an initiative under the Center of Innovation Science and Technology based Radical Innovation and Entrepreneurship Program (COI STREAM) of the Ministry of Education, Culture, Sports, Science and Technology, Japan.

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