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論文・その他(図書・総説） 2015年度

論文　|　その他(総説・図書）

論文

No. タイトル・発表者等 発表機関
1 Sugaya, A., Hyodo, I., Koga, Y., Yamamoto, Y., Takashima, H., Sato, R., Tsumura, R., Furuya, F., Yasunaga, M., Harada, M., Tanaka, R., and Matsumura, Y., Utility of epirubicin-incorporating micelles tagged with anti-tissue factor antibody clone with no anticoagulant effect, Cancer Sci., doi:10.1111/cas.12863, 2016 国立がん研究センター、
ナノキャリア株式会社
2 Koga Y, Manabe S, Aihara Y, Sato R, Tsumura R, Iwafuji H, Furuya F, Fuchigami H, Fujiwara Y, Hisada Y, Yamamoto Y, Yasunaga M, Matsumura Y, Antitumor effect of anti-tissue factor antibody-MMAE conjugate in human pancreatic tumor xenografts, Int J Cancer, 137(6):1457-1466, 2015. 国立がん研究センター、　
理化学研究所
3 Yamamoto Y, Hyodo I, Koga Y, Tsumura R, Sato R, Obonai T, Fuchigami H, Furuya F, Yasunaga M, Harada M, Kato Y, Ohtsu A, Matsumura Y, Enhanced antitumor effect of anti-tissue factor (TF) antibody-conjugated epirubicin-incorporating polymeric micelles in human cancer xenografts with high TF expression, Cancer Sci, 106(5):627-634, 2015. 国立がん研究センター、　
ナノキャリア株式会社
4 Tsumura R, Sato R, Furuya F, Koga Y, Yamamoto Y, Fujiwara Y, Yasunaga M, Matsumura Y, Feasibility study of the Fab fragment of a monoclonal antibody against tissue factor as a diagnostic tool, Int J Oncol, 47(6):2107-2114, 2015. 国立がん研究センター
5 Sugaya A, Hyodo I, Koga Y, Yamamoto Y, Takashima H, Sato R, Tsumura R, Furuya F, Yasunaga M, Harada M, Tanaka R, Matsumura Y, Utility of epirubicin-incorporating micelle tagged with anti-tissue factor antibody clone with no anticoagulant effect, Cancer Sci, 2015  国立がん研究センター、
ナノキャリア株式会社
6 L. Cui, K. Osada, A. Imaizumi, K. Kataoka, K. Nakano, Feasibility of a subcutaneously administered block/homo-mixed polyplex micelle as a carrier for DNA vaccination in a mouse tumor model, J. Control. Release, 206, 220-231, DOI: 10.1016/j.jconrel.2015.03.029, 2015 国立大学法人東京大学
7 N. Q. Vinh, S. Naka, H. Cabral, H. Murayama, S. Kaida, K. Kataoka, S. Morikawa, T. Tani, MRI-detectable polymeric micelles incorporating platinum anticancer drugs enhance survival in an advanced hepatocellular carcinoma model, Int. J. Nanomedicine, 10, 4137-4147, DOI: 10.2147/IJN.S81339, 2015 国立大学法人東京大学
8 J. Li, Q. Chen, Z. Zha, H. Li, K. Toh, A. Dirisala, Y. Matsumoto, K. Osada, K. Kataoka, Z. Ge, Ternary polyplex micelles with PEG shells and intermediate barrier to complexed DNA cores for efficient systemic gene delivery, J. Control. Release, 209, 77-87, DOI: 10.1016/j.jconrel.2015.04.024, 2015 国立大学法人東京大学
9 O. F. Mutaf, A. Kishimura, Y. Mochida, A. Kim, K. Kataoka, Induction of secondary structure through micellization of an oppositely charged pair of homochiral block- and homopolypeptides in an aqueous medium, Macromol. Rapid Commun., 36, 1958-1964, DOI: 10.1002/marc.201500368, 2015 国立大学法人東京大学
10 S. Osawa, K. Osada, S. Hiki, A. Dirisala, T. Ishii, K. Kataoka, Polyplex micelles with double-protective compartments of hydrophilic shell and thermo-switchable palisade of poly(oxazoline)-based block copolymers for promoted gene transfection, Biomacromolecules, 17, 354-361, DOI: 10.1021/acs.biomac.5b01456, 2016 国立大学法人東京大学
11 H. Hosoya, A. S. Dobroff, W. H. P. Driessen, V. Cristini, L. M. Brinker, F. I. Staquicini, M. C.-Vila, S. D’Angelo, F. Ferrara, B. Proneth, Y.-S. Lin, D. R. Dunphy, P. Dogra, M. P. Melancon, R. J. Stafford, K. Miyazono, J. G. Gelovani, K. Kataoka, C. J. Brinker, R. L. Sidman, W. Arap, R. Pasqualini, Integrated nanotechnology platform for tumor-targeted multimodal imaging and therapeutic cargo release, Proc. Natl. Acad. Sci. USA., 113, 1877-1882, DOI: 10.1073/pnas.1525796113, 2016 国立大学法人東京大学
12 D. L. Stirland, Y. Matsumoto, K. Toh, K. Kataoka, Y. -H. Bae, Analyzing spatiotemporal distribution of uniquely fluorescent nanoparticles in xenograft tumors, J. Control. Release, 227, 38-44, DOI: 10.1016/j.jconrel.2016.02.016, 2016 国立大学法人東京大学
13 T. A. Tockary, K. Osada, Y. Motoda, S. Hiki, Q. Chen, K. M. Takeda, A. Dirisala, S. Osawa, K. Kataoka, Rod-to-globule transition of pDNA/PEG-Poly(L-lysine) polyplex micelles induced by a collapsed balance between DNA rigidity and PEG crowdedness, Small, 12, 1193-1200, DOI: 10.1002/smll.201501815, 2016 国立大学法人東京大学
14 T. Aimi, K. Suzuki, T. Hoshino and T. Mizushima. Dextran sulfate sodium inhibits amyloid-β oligomer binding to cellular prion protein. J.Neurochem.134(4), 611-617, doi: 10.1111/jnc.13166. Epub 2015 Jun 10.　 慶應義塾大学
15 K. Suzuki, T. Aimi, T. Ishihara and T. Mizushima. Identification of approved drugs that inhibit the binding of amyloid β oligomers to ephrin type-B receptor 2. FEBS Open Bio. 慶應義塾大学
16 Anraku Y, Kuwahara H, Fukusato Y, Mizoguchi A, Ishii T, Nitta K, Matsumoto Y, Toh K, Miyata K, Uchida S, Nishina K, Osada K, Itaka K, Nishiyama N, Mizusawa H, Yokota T, Kataoka T. Crossing the BBB: Glycemic control boosts glucosylated nanocarrier transport into brain. Nat Nanotechnol. 国立大学法人東京大学、
東京医科歯科大学
17 Y. Anraku, A. Kishimura, M. Kamiya, S. Tanaka, T. Nomoto, K. Toh, Y. Matsumoto, S. Fukushima, D. Sueyoshi, M. R. Kano, Y. Urano, N. Nishiyama, K. Kataoka, Systemically injectable enzyme-loaded polyion complex vesicles as in vivo nanoreactors functioning in tumors, Angew. Chem. Int. Ed., 128, 570-575, DOI: 10.1002/ange.201508339, 2016 国立大学法人東京大学
18 Soulard V, Bosson-Vanga H, Lorthiois A, et al. Plasmodium falciparum full life cycle and Plasmodium ovale liver stages in humanized mice. Nat Commun 2015;6:7690. (公財）実験動物中央研究所
19 Adachi K, Suemizu H, Murayama N, Shimizu M, Yamazaki H. Human biofluid concentrations of mono(2-ethylhexyl)phthalate extrapolated from pharmacokinetics in chimeric mice with humanized liver administered with di(2-ethylhexyl)phthalate and physiologically based pharmacokinetic modeling. Environ Toxicol Pharmacol 2015;39(3):1067-73. (公財）実験動物中央研究所
20 Hikishima K, Ando K, Komaki Y, Kawai K, Yano R, Inoue T, Itoh T, Yamada M, Momoshima S, Okano HJ, Okano H. Voxel-based morphometry of the marmoset brain: In vivo detection of volume loss in the substantia nigra of the MPTP-treated Parkinson's disease model. Neuroscience. 2015 May 23;300:585-592 (公財）実験動物中央研究所
21 Hikishima K, Ando K, Yano R, Kawai K, Komaki Y, Inoue T, Itoh T, Yamada M, Momoshima S, Okano HJ, Okano H. Parkinson Disease: Diffusion MR Imaging to Detect Nigrostriatal Pathway Loss in a Marmoset Model Treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Radiology. 2015 May;275(2):430-7. (公財）実験動物中央研究所
22 Hata, J. , Nagata, H. , Endo, K. , Komaki, Y. , Sato, M. , Numano, T. and Yagi, K. Assessment of Human Skeletal Muscle Contraction and Force by Diffusion Tensor Imaging. Open Journal of Radiology, 5, 189-198. (公財）実験動物中央研究所
23  Higuchi Y, Kawai K, Kanaki T, et al. Functional polymer-dependent 3D culture accelerates the differentiation of HepaRG cells into mature hepatocytes. Hepatol Res 2016. inpress (公財）実験動物中央研究所
24 Yokoyama Y, Miyagi T, Hikita H, et al. The Hepatitis B Virus Genotype Affects the Persistence of Viral Replication in Immunodeficient NOG Mice. PloS one 2015;10(12):e0144775. (公財）実験動物中央研究所
25  Nishime C, Kawai K, Yamamoto T, et al. Innate Response to Human Cancer Cells with or without IL-2 Receptor Common gamma-Chain Function in NOD Background Mice Lacking Adaptive Immunity. J Immunol 2015;195:1883-90. (公財）実験動物中央研究所
26  Miyaguchi T, Suemizu H, Shimizu M, et al. Human urine and plasma concentrations of bisphenol A extrapolated from pharmacokinetics established in in vivo experiments with chimeric mice with humanized liver and semi-physiological pharmacokinetic modeling. Regul Toxicol Pharmacol 2015;72(1):71-6. (公財）実験動物中央研究所
27  Katano I, Takahashi T, Ito R, et al. Predominant Development of Mature and Functional Human NK Cells in a Novel Human IL-2-Producing Transgenic NOG Mouse. J Immunol 2015;194(7):3513-25. (公財）実験動物中央研究所
28  Kamimura H, Ito S, Nozawa K, et al. Formation of the Accumulative Human Metabolite and Human-Specific Glutathione Conjugate of Diclofenac in TK-NOG Chimeric Mice with Humanized Livers. Drug Metab Dispos 2015;43(3):309-16. (公財）実験動物中央研究所
29 Kai Y, Hikita H, Tatsumi T, et al. Emergence of hepatitis C virus NS5A L31V plus Y93H variant upon treatment failure of daclatasvir and asunaprevir is relatively resistant to ledipasvir and NS5B polymerase nucleotide inhibitor GS-558093 in human hepatocyte chimeric mice. J Gastroenterol 2015;50(11):1145-51. (公財）実験動物中央研究所
30 Hashimoto H, Kamisako T, Kagawa T, et al. Expression of pancreatic and duodenal homeobox1 (PDX1) protein in the interior and exterior regions of the intestine, revealed by development and analysis of Pdx1 knockout mice. Lab Anim Res 2015;31(2):93-8. (公財）実験動物中央研究所
31 Takata N, Yoshida K, Komaki Y, Xu M, Sakai Y, Hikishima K, Mimura M, Okano H, Tanaka KF. Optogenetic activation of CA1 pyramidal neurons at the dorsal and ventral hippocampus evokes distinct brain-wide responses revealed by mouse fMRI. PLoS One. 2015 Mar 20;10(3) (公財）実験動物中央研究所
32 Shibata S, Komaki Y, Seki F, Inouye MO, Nagai T, Okano H. Connectomics: comprehensive approaches for whole-brain mapping. Microscopy (Oxf). 2015 Feb;64(1):57-67. (公財）実験動物中央研究所
33  Shimada S, Nunomura S, Mori S, et al. Common marmoset CD117+ hematopoietic cells possess multipotency. Int Immunol 2015;27(11):567-77. (公財）実験動物中央研究所
34  Nishiyama S, Suemizu H, Shibata N, Guengerich FP, Yamazaki H. Simulation of Human Plasma Concentrations of Thalidomide and Primary 5-Hydroxylated Metabolites Explored with Pharmacokinet-ic Data in Humanized TK-NOG mice. Chemical research in toxicology 2015;28(11):2088–90. (公財）実験動物中央研究所
35 Chijiwa T, Kawai K, Noguchi A, et al. Establishment of patient-derived cancer xenografts in immunodeficient NOG mice. Int J Oncol 2015;47(1):61-70. (公財）実験動物中央研究所
36 S. Uchida, K. Kataoka, K. Itaka, Screening of mRNA chemical modification to maximize protein expression with reduced immunogenicity, Pharmaceutics, 7, 137-151, DOI: 10.3390/pharmaceutics7030137, 2015 国立大学法人東京大学
37 K. Itaka, S. Uchida, A. Matsui, K. Yanagihara, M. Ikegami, T. Endo, T. Ishii, K. Kataoka, Gene transfection toward spheroid cells on micropatterned culture plates for genetically-modified cell transplantation, JoVE, 101, DOI: 10.3791/52384, 2015 国立大学法人東京大学
38 Y. Li, K. Osada, Q. Chen, T. A. Tockary, A. Dirisala, K. M. Takeda, S. Uchida, K. Nagata, K. Itaka, K. Kataoka, Toroidal packaging of pDNA into block ionomer micelles exerting promoted in vivo gene expression, Biomacromolecules, 16, 2664-2671, DOI: 10.1021/acs.biomac.5b00491, 2015 国立大学法人東京大学
39 A. Matsui, S. Uchida, T. Ishii, K. Itaka, K. Kataoka, Messenger RNA-based therapeutics for the treatment of apoptosis-associated diseases, Sci. Rep., 5, DOI: 10.1038/srep15810, published on line 国立大学法人東京大学
40 H. Aini, K. Itaka, A. Fujisawa, H. Uchida, S. Uchida, S. Fukushima, K. Kataoka, T. Saito, U. -I. Chung, S. Ohba, Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment, Sci. Rep., 6, DOI: 10.1038/srep18743, 2016 国立大学法人東京大学
41 矢野竜太朗、畑純一、関布美子、石原良祐、小牧裕司、疋島啓吾、田中謙二、岡野栄之：超高磁場MRIで脱髄を追う；日本磁気共鳴医学会雑誌Vol.36,No.1（査読なし） (公財）実験動物中央研究所
42 Tominaga N, Kosaka N, Ono M, Katsuda T, Yoshioka Y, Tamura K, Lötvall J, Nakagama H, Ochiya T. Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood-brain barrier. Nat. Commun, 6: 6716, 2015 国立がん研究センター
43 Hagiwara K, Katsuda T, Gailhouste L, Kosaka N, Ochiya T. Commitment of Annexin A2 in recruitment of microRNAs into extracellular vesicles; FEBS Lett, 589: 4071-4078, 2015 国立がん研究センター
44 Fujita Y, Araya J, Ito S, Kobayashi K, Kosaka N, Yoshioka Y, Kadota T, Hara H, Kuwano K, Ochiya T. Suppression of autophagy by extracellular vesicles promotes myofibroblast differentiation in COPD pathogenesis. J Extracell Vesicles, 4:28388, 2015 国立がん研究センター
45 Yoshioka Y, Katsuda T, Ochiya T. Circulating microRNAs as Hormones: Intercellular and Inter-organ Conveyors of Epigenetic Information? Experientia Supplementum. 106:255-267, 2015 国立がん研究センター
46 Goda T, Yamada E, Katayama Y, Tabata M, Matsumoto A, Miyahara Y, Potentiometric Responses of Ion-Selective Microelectrode with Bovine Serum Albumin Adsorption, Biosens. Bioelectron., 2016, 77, 208-214. DOI: 10.1016/j.bios.2015.09.023 東京医科歯科大学
47 Goda T, Toya M, Matsumoto M, Miyahara Y, "Poly(3,4-ethylenedioxythiophene) Bearing Phosphorylcholine Groups for Metal-free, Antibody-free, and Low-impedance Biosensors Sspecific for C-reactive Protein", ACS Appl. Mater. Interfaces, 2015, 7(49), 27440-27448. DOI: 10.1021/acsami.5b09325. 東京医科歯科大学
48 Goda T, Higashi D, Matsumoto A, Hoshi T, Sawaguchi T, Miyahara Y, "Dual Aptamer-Immobilized Surfaces for Improved Affinity through Multiple Target Binding in Potentiometric Thrombin Biosensing", Biosens. Bioelectron., 2015, 73, 174-180. DOI: 10.1016/j.bios.2015.05.067 東京医科歯科大学
49 Goda T, Tabata M, Miyahara Y, "Electrical and Electrochemical Monitoring of Nucleic Acid Amplification", Frontiers in Bioengineering and Biotechnology 3, 29 (2015). DOI: 10.3389/fbioe.2015.00029 東京医科歯科大学
50 Ayaka Seichi, Nanami Kozuka, Yuko Kashima, Miyuki Tabata, Tatsuro Goda, Akira Matsumoto, Naoko Iwasawa, Daniel Citterio, Yuji Miyahara, Koji Suzuki, “Real-time Monitoring and Detection of Primer Generation-rolling Circle Amplification of DNA using an Ethidium Ion Selective Electrode”, Anal. Sci. accepted. 東京医科歯科大学
51 Mai Sanjoh, Daisuke Iizuka, Akira Matsumoto and Yuji Miyahara,
"Boronate Based Metal-Free Platform for Diphosphate-Specific Molecular Recognitions", 
Org. Lett., 2015, 17(3), 588-591. 東京医科歯科大学
52 Akira Matsumoto, Mai Yuasa, Mai Sanjo, Miyuki Tabata, Tatsuro Goda, Toru Hoshi, Takao Aoyagi, Yuji Miyahara, "Boronate Functionalized Polymer Gel Based Insulin Delivery System with Improved Stability in Performance: A Comparative Structure-Function Study", Chem. Lett. accepted. 東京医科歯科大学
53 C. Jiang, K. Uto, M. Ebara, T. Aoyagi, and T. Ichiki, “Implementation of poly(e-caprolactone) sheet-based shape-memory microvalves into plastic-based microfluidic devices”, Jpn. J. Appl. Phys. 54, 06FN02 (2015). 国立大学法人東京大学
54 T. Akagi, K. Kato, M. Kobayashi, N. Kosaka, T. Ochiya, and T. Ichiki, “On-chip immunoelectrohoresis of extracellular vesicles released from human breast cancer cells”, PLOS ONE 10, e0123603 (2015). 国立大学法人東京大学、
国立がん研究センター
55 T. Akagi, R. Kubota, M. Kobayashi, and T. Ichiki, “Development of a polymer-based easy-to-fabricate micro-free-flow electrophoresis devices”, Jpn. J. Appl. Phys. 54, 06FN05 (2015). 国立大学法人東京大学
56 T. Akagi, N. Hanamura and T. Ichiki, “Measurement of individual nanobioparticles on microfluidic chips by laser dark-field imaging”, J. Photopolymer Sci. Technol. 5, pp. 727-730 (2015). 国立大学法人東京大学
57 一木隆範、赤木貴則、「ナノ医療を加速するナノ粒子解析プラットフォームの開発」、Drug Delivery System　30( 3), pp. 113-118 (2015). 国立大学法人東京大学
58 一木隆範、バイオチップの基礎と応用　第II編第1章4節「分泌型miRNA診断デバイスの開発」、シーエムシー出版 (分担執筆) pp. 53-59 (2015). 国立大学法人東京大学
59 Kanamori, T., T. Funatsu, and M. Tsunoda, Evaluation of the Effects of Sample Solutions and Injector Wash Solutions on Separation Efficiency in Hydrophilic Interaction Liquid Chromatography, Chromatography, 36: 123-126, doi:10.15583/jpchrom.2015.028, 2013. 国立大学法人東京大学
60 Nakamura, K., R. Iizuka, S. Nishi, T. Yoshida, Y. Hatada, Y. Takaki, A. Iguchi, D. H. Yoon, T. Sekiguchi, S. Shoji, and T. Funatsu, Culture-independent method for identification of microbial enzyme-encoding genes by activity-based single-cell sequencing using a water-in-oil microdroplet platform, Sci. Rep. 6: 22259, dio:10.1038/srep22259, 2016 国立大学法人東京大学
61 Isokawa, M., T. Shimosawa, T. Funatsu and M. Tsunoda, Determination and characterization of total thiols in mouse serum samples using hydrophilic interaction liquid chromatography with fluorescence detection and mass spectrometry, J. Chromatgr. B, in press, doi:10.1016/j.jchromb.2015.11.038 国立大学法人東京大学
62 Kondo, E., Wada, K.-I., Hosokawa, K., Maeda, M., Cryopreservation of adhered mammalian cells on a microfluidic device: toward ready-to-use cell-based experimental platforms, Biotechnology and Bioengineering, 113, 237-240, 2016 理化学研究所
63 Wada, K.-I., Hosokawa, K., Ito, Y., Maeda, M., Effects of ROCK inhibitor Y-27632 on cell fusion through a microslit, Biotechnology and Bioengineering, 112, 2334-2342, 2015 理化学研究所
64 Ishihara, R., Hasegawa, K., Hosokawa, K., Maeda, M., Multiplex microRNA detection on a power-free microfluidic chip with laminar flow-assisted dendritic amplification, Analytical Sciences, 31, 573-576, 2015 理化学研究所
65 Lee, S. W., Hosokawa, K., Kim, S., Jeong, O. C., Lilja, H., Laurell, T., Maeda, M., Highly sensitive porous silicon (P-Si) based human kallikrein 2 (hK2) immunoassay platform toward accurate diagnosis of prostate cancer, Sensors, 15, 11972-11987, 2015 理化学研究所
66 石原量，長谷川和貴，細川和生，前田瑞夫；自律駆動マイクロ流体チップと層流樹状増幅法によるタンパク質と核酸の検出，分析化学, 64, 319-328, 2015 理化学研究所
67 Yokoi A, Yoshioka Y, Ochiya T. Towards the realization of clinical extracellular vesicle diagnostics: challenges and opportunities; Expert Rev Mol Diagn, 15:1555-66, 2015 国立がん研究センター
68 Fujihara A, Shimada N, Maruyama A, Ishihara K, Nakai K, Yusa S-i. Preparation of upper critical solution temperature (UCST) responsive diblock copolymers bearing pendant ureido groups and their micelle formation behavior in water. Soft Matter. 11, 5204-5213,2015. DOI: 10.1039/C5SM00499C 東京工業大学
69 Gao J, Shimada N, Maruyama A. Enhancement of deoxyribozyme activity by cationic copolymers. Biomater. Sci., 3, 308-316, 2015. DOI: 10.1039/C4BM00256C 東京工業大学
70 Gao J, Shimada N, Maruyama A. MNAzyme-catalyzed nucleic acid detection enhanced by a cationic copolymer. Biomater. Sci. 2015;3:716-20. DOI: 10.1039/C4BM00449C 東京工業大学
71 Shimada N, Kinoshita H, Tokunaga S, Umegae T, Kume N, Sakamoto W, et al. Inter-polyelectrolyte nano-assembly induces folding and activation of functional peptides. J. Contr. Release. 218,45-52,2015,DOI:10.1016/j.jconrel.2015.10.001  東京工業大学
72 Mi, P., D. Kokuryo, H. Cabral, H. Wu, Y. Terada, T. Saga, I. Aoki, N. Nishiyama, K. Kataoka, A contrast amplification strategy for non-invasive imaging of tumor malignancy with activatable nanoparticles, Nature Nanotech., in press, 2016 ナノ医療イノベーションセンター、
国立大学法人東京大学、
東京工業大学、
放射線医学総合研究所
73 Nomoto, T., S. Fukushima,M. Kumagai, K. Miyazaki, A. Inoue, P. Mi, Y. Maeda, K. Toh, Y. Matsumoto, Y. Morimoto, A. Kishimura, N. Nishiyama, K. Kataoka, Biomaterials Science, in press, 2016 ナノ医療イノベーションセンター、
国立大学法人東京大学、
東京工業大学
74 Dewi, N., P. Mi, H. Yanagie, Y. Sakurai, Y. Morishita, M. Yanagawa, T. Nakagawa, A. Shinohara, T. Matsukawa, K. Yokoyama, H. Cabral, M. Suzuki, Y. Sakurai, H. Tanaka, K. Ono, N. Nishiyama, K. Kataoka, H. Takahashi, In vivo evaluation of neutron capture therapy effectivity using calcium phosphate-based nanoparticles as Gd-DTPA delivery agent. J. Cancer Res. Clin. Oncol. in press, doi: 10.1007/s00432-015-2085-0, 2016 ナノ医療イノベーションセンター、
国立大学法人東京大学、
東京工業大学、
放射線医学総合研究所
75 Anraku, Y., A. Kishimura, M. Kamiya, S. Tanaka, T. Nomoto, K. Toh, Y. Matsumoto, S. Fukushima, D. Sueyoshi, M. R. Kano, Y. Urano, N. Nishiyama, K. Kataoka, Systemically injectable enzyme-loaded polyion complex vesicles as in vivo nanoreactors functioning in tumors. Angew. Chem. Int. Ed. 128 (2) 570-575, doi: 10.1002/ange.201508339, 2016 国立大学法人東京大学、
東京工業大学
76 Miura, Y., A. B. Tsuji, A. Sugyo, H. Sudo, I. Aoki, M. Inubushi, M. Yashiro, K. Hirakawa, H. Cabral, N. Nishiyama, T. Saga, K. Kataoka, Polymeric micelle platform for multimodal tomographic imaging to detect scirrhous gastric cancer. ACS Biomater. Sci. Eng. 1 (11) 1067-1076, doi:10.1021/acsbiomaterials.5b00142, 2015 ナノ医療イノベーションセンター、
国立大学法人東京大学、
東京工業大学、
放射線医学総合研究所
77 Mi, P., N. Dewi, H. Yanagie, D. Kokuryo, M. Suzuki, Y. Sakurai, Y. Li, I. Aoki, K. Ono, H. Takahashi, H. Cabral, N. Nishiyama, K. Kataoka, Hybrid calcium phosphate-polymeric micelles incorporating gadolinium chelates for imaging-guided gadolinium neutron capture tumor therapy. ACS Nano 9 (6) 5913-5921, doi: 10.1021/acsnano.5b00532, 2015 ナノ医療イノベーションセンター、
国立大学法人東京大学、
東京工業大学、
放射線医学総合研究所
78 Kawamura, W., Y. Miura, D. Kokuryo, K. Toh, N. Yamada, T. Nomoto, Y. Matsumoto, D. Sueyoshi, X. Liu, I. Aoki, M. R. Kano, N. Nishiyama, T. Saga, A. Kishimura, K. Kataoka*, Density-tunable conjugation of cyclic RGD ligands with polyion complex vesicles for the neovascular imaging of orthotopic glioblastomas. Sci. Technol. Adv. Mater. 16 (3) 035004, doi: 10.1088/1468-6996/16/3/035004, 2015 ナノ医療イノベーションセンター、
国立大学法人東京大学、
東京工業大学、
放射線医学総合研究所
79 Murayama S, Jo J, Arai K, Nishikido F, Bakalova R, Yamaya T, Saga T, Kato M, Aoki I. γ-PARCEL: Control of Molecular Release Using γ-Rays. Anal Chem. 2015 Dec 1;87(23):11625-9. doi: 10.1021/acs.analchem.5b03030. Epub 2015 Nov 16. PubMed PMID: 26525641. 放射線医学総合研究所
80 Miura Y, Tsuji A, Sugyo A, Sudo H, Aoki I, Inubushi, M, Yashiro M, Hirakawa K, Cabral H, Nishiyama N, Saga T, Kataoka K. Polymeric Micelle Platform for Multimodal Tomographic Imaging to Detect Scirrhous Gastric Cancer. ACS Biomater Sci Eng, 2015, 1 (11):1067-76. doi: 10.1021/acsbiomaterials.5b00142. 国立大学法人東京大学、
放射線医学総合研究所、
東京工業大学
81 Aoki I,* Yoneyama M, Hirose J, Minemoto Y, Koyama T, Kokuryo D, Bakalova R, Murayama S, Saga T, Aoshima S, Ishizaka Y, Kono K. Thermoactivatable polymer-grafted liposomes for low-invasive image-guided chemotherapy. Transl Res. 2015 Dec;166(6):660-673.e1. doi: 10.1016/j.trsl.2015.07.009. Epub 2015 Aug 6. PubMed PMID: 26303887. 放射線医学総合研究所
82 Mi P, Dewi N, Yanagie H, Kokuryo D, Suzuki M, Sakurai Y, Li Y, Aoki I, Ono K, Takahashi H, Cabral H, Nishiyama N, Kataoka K. Hybrid Calcium Phosphate-Polymeric Micelles Incorporating Gadolinium Chelates for Imaging-Guided Gadolinium Neutron Capture Tumor Therapy. ACS Nano. 2015 Jun 23;9(6):5913-21. doi:10.1021/acsnano.5b00532. Epub 2015 Jun 11. PubMed PMID: 26033034. ナノ医療イノベーションセンター、
放射線医学総合研究所、
国立大学法人東京大学、
東京工業大学
83 Sawada K, Horiuchi-Hirose M, Saito S, Aoki I. Sexual dimorphism of sulcal morphology of the ferret cerebrum revealed by MRI-based sulcal surface morphometry. Front Neuroanat. 2015 May 6;9:55. doi: 10.3389/fnana.2015.00055. eCollection 2015. PubMed PMID: 25999821; PubMed Central PMCID: PMC4422084. 放射線医学総合研究所
84 Kawamura W, Miura Y, Kokuryo D, Toh K, Yamada N, Nomoto T, Matsumoto Y, Aoki I, Kano MR, Nishiyama N, Saga T, Kishimura A, Kataoka K*. Density-tunable conjugation of cyclic RGD ligands with polyion complex vesicles for the neovascular imaging of orthotopic glioblastomas. Sci Technol Adv Mater. 2015 June;16(3) 035004:1-13. doi:10.1088/1468-6996/16/3/035004 国立大学法人と京大学、
放射線医学総合研究所、
東京工業大学
85 味の素株式会社のオープンイノベーションとiCONM（ナノ医療イノベーションセンター）への期待　黒澤　渉　Drug Delivery System, 30(3), 194-203, 2015 味の素株式会社
86 村垣善浩、前田真法、伊関洋、岡本淳、岸本眞治、正宗賢、吉澤晋、梅村晋一郎医工連携と癌治療　国産DDS製剤と集束超音波治療装置による音響力学的療法の実現、日本癌治療学会誌、2015 東京女子医科大学
87 H. Cabral, J. Makino, Y. Matsumoto, P. Mi, H. Wu, T. Nomoto, K. Toh, N. Yamada, Y. Higuchi, S. Konishi, M. R. Kano, H. Nishihara, Y. Miura, N. Nishiyama, K. Kataoka, Systemic targeting of lymph node metastasis through the blood vascular system by using size-controlled nanocarriers, ACS Nano, 9, 4957-4967, DOI: 10.1021/nn5070259, 2015 国立大学法人東京大学
88 K. S. -Kato, K. Nanjo, H. Kusuhara, N. Nishiyama, K. Kataoka, T. Kawanishi, H. Okuda, Y. Goda, Effect of knockout of Mdr1a and Mdr1b ABCB1 genes on the systemic exposure of a doxorubicin-conjugated block copolymer in mice, Mol. Pharmaceutics, 12, 3175-3183, DOI: 10.1021/acs.molpharmaceut.5b00234, 2015 国立大学法人東京大学
89 Y. Miura, A. B. Tsuji, A. Sugyo, H. Sudo, I. Aoki, M. Inubushi, M. Yashiro, K. Hirakawa, H. Cabral, N. Nishiyama, T. Saga, K. Kataoka, Polymeric micelle platform for multimodal tomographic imaging to detect scirrhous gastric cancer, ACS Biomater. Sci. Eng., 1, 1067-1076, DOI: 10.1021/acsbiomaterials.5b00142, 2015 国立大学法人東京大学
90 A. Kim, Y. Miura, T. Ishii, O. F. Mutaf, N. Nishiyama, H. Cabral, K. Kataoka, Intracellular delivery of charge-converted monoclonal antibodies by combinatorial design of block/homo polyion complex micelles, Biomacromolecules, 17, 446-453, DOI: 10.1021/acs.biomac.5b01335, 2016 国立大学法人東京大学
91 H. Uchida, K. Itaka, S. Uchida, T. Ishii, T. Suma, K. Miyata, M. Oba, N. Nishiyama, K. Kataoka, Synthetic polyamines to regulate mRNA translation through the preservative binding of eukaryotic initiation factor 4E to the cap structure, J. Am. Chem. Soc., 138, 1478–1481, DOI: 10.1021/jacs.5b11726, 2016 国立大学法人東京大学
92 N. Dewi, P. Mi, H. Yanagie, Y. Sakurai, Y. Morishita, M. Yanagawa, T. Nakagawa, A. Shinohara, T. Matsukawa, K. Yokoyama, H. Cabral, M. Suzuki, Y. Sakurai, H. Tanaka, K. Ono, N. Nishiyama, K. Kataoka, H. Takahashi, In vivo evaluation of neutron capture therapy effectivity using calcium phosphate-based nanoparticles as Gd-DTPA delivery agent, J. Cancer Res. Clin. Oncol., 142, 767-775, DOI: 10.1007/s00432-015-2085-0, 2016 国立大学法人東京大学
93 Anzai, T., Sengoku, S., Managing Academic Interdisciplinary Research towards Innovation: A Resource and Communication-Based Approach, Technology Transfer and Entrepreneurship. 国立大学法人東京大学、
東京工業大学
94 Anzai, T., Sengoku, S., Managing Academic Interdisciplinary Research towards Innovation: A Resource and Communication-Based Approach, Technology Transfer and Entrepreneurship. 国立大学法人東京大学、
東京工業大学
95 Matsumoto Y., J. W. Nichols, K. Toh, T. Nomoto, H. Cabral, Y. Miura, R. J. Christie, N. Yamada, T. Ogura, M. R. Kano, Y. Matsumura, N. Nishiyama, T. Yamasoba, Y. -H. Bae, K. Kataoka, Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery. Nature Nanotech. in press, doi: 10.1038/nnano.2015.342, 2016 ナノ医療イノベーションセンター、
国立大学法人東京大学、
東京工業大学
96 T. Ishii, K. Miyata, Y. Anraku, M. Naito, Y. Yi, T. Jinbo, S. Takae, Y. Fukusato, M. Hori, K. Osada, K. Kataoka, Enhanced target recognition of nanoparticles by cocktail PEGylation with chains of varying lengths, Chem. Commun., 52, 1517-1519, DOI: 10.1039/C5CC06661A, 2016 国立大学法人東京大学
97 T. Okuda, Y. Suzuki, Y. Kobayashi, T. Ishii, S. Uchida, K. Itaka, K. Kataoka, H. Okamoto, Development of biodegradable polycation-based inhalable dry gene powders by spray freeze drying, Pharmaceutics, 7, 233-254, DOI: 10.3390/pharmaceutics7030233, 2015 国立大学法人東京大学
98 H. Ogawa, X. Wu, K. Kawamoto, N. Nishida, M. Konno, J. Koseki, H. Matsui, K. Noguchi, N. Gotoh, T. Yamamoto, K. Miyata, N. Nishiyama, H. Nagano, H. Yamamoto, S. Obika, K. Kataoka, Y. Doki, M. Mori, H. Ishii , MicroRNAs induce epigenetic reprogramming and suppress malignant phenotypes of human colon cancer cells, PLOS ONE, 10(5), e0127119, DOI: 10.1371/journal.pone.0127119, 2015 国立大学法人東京大学
99 W. Kawamura, Y. Miura, D. Kokuryo, K. Toh, N. Yamada, T. Nomoto, Y. Matsumoto, D. Sueyoshi, X. Liu, I. Aoki, M. R. Kano, N. Nishiyama, T. Saga, A. Kishimura, K. Kataoka, Density-tunable conjugation of cyclic RGD ligands with polyion complex vesicles for the neovascular imaging of orthotopic glioblastomas, Sci. Technol. Adv. Mater., 16, 035004, DOI: 10.1088/1468-6996/16/3/035004, 2015 国立大学法人東京大学
100 P. Mi, N. Dewi, H. Yanagie, D. Kokuryo, M. Suzuki, Y. Sakurai, Y. Li, I. Aoki, K. Ono, H. Takahashi, H. Cabral, N. Nishiyama, K. Kataoka, Hybrid calcium phosphate-polymeric micelles incorporating gadolinium chelates for imaging-guided gadolinium neutron capture tumor therapy, ACS Nano, 9, 5913-5921, DOI: 10.1021/acsnano.5b00532, 2015 国立大学法人東京大学
101 K. Nishina, W. Piao, K. Y-Tanaka, Y. Sujino, T. Nishina, T. Yamamoto, K. Nitta, K. Yoshioka, H. Kuwahara, H. Yasuhara, T. Baba, F. Ono, K. Miyata, K. Miyake, P. P. Seth, A. Low, M. Yoshida, C. F. Bennett, K. Kataoka, H. Mizusawa, S. Obika, T. Yokota, DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing, Nat. Commun., 6, DOI: 10.1038/ncomms8969, 2015 国立大学法人東京大学
102 M. Murakami, K. Nishina, C. Watanabe, K. Y. Tanaka, W. Piao, H. Kuwahara, Y. Horikiri, K. Miyata, N. Nishiyama, K. Kataoka, M. Yoshida, H. Mizusawa, T. Yokota, Enteral siRNA delivery technique for therapeutic gene silencing in the liver via the lymphatic route, Sci. Rep., 5, DOI: 10.1038/srep17035, 2015 国立大学法人東京大学
103 J. Makino, H. Cabral, Y. Miura, Y. Matsumoto, M. Wang, H. Kinoh, Y. Mochida, N. Nishiyama, K. Kataoka, cRGD-installed polymeric micelles loading platinum anticancer drugs enable cooperative treatment against lymph node metastasis, J. Control. Release, 220, 783-791, DOI: 10.1016/j.jconrel.2015.10.017, 2015 国立大学法人東京大学
104 M. Tangsangasaksri, H. Takemoto, M. Naito, Y. Maeda, D. Sueyoshi, H. -J. Kim, Y. Miura, J. -Y. Ahn, R. Azuma, N. Nishiyama, K. Miyata, K. Kataoka, siRNA-loaded polyion complex micelle decorated with charge-conversional polymer tuned to undergo stepwise response to intra-tumoral and intra-endosomal pHs for exerting enhanced RNAi efficacy, Biomacromolecules, 17, 246-255, DOI: 10.1021/acs.biomac.5b01334, 2016 国立大学法人東京大学
105 K. Hayashi, H. Chaya, S. Fukushima, S. Watanabe, H. Takemoto, K. Osada, N. Nishiyama, K. Miyata, K. Kataoka, Influence of RNA strand rigidity on polyion complex formation with block catiomers, Macromol. Rapid Commun., 37, 486-493, DOI: 10.1002/marc.201500661, 2016 国立大学法人東京大学
106 Y. Matsumoto, J. W. Nichols, K. Toh, T. Nomoto, H. Cabral, Y. Miura, R. J. Christie, N. Yamada, T. Ogura, M. R. Kano, Y. Matsumura, N. Nishiyama, T. Yamasoba, Y. -H. Bae, K. Kataoka, Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery, Nat. Nanotechnol., DOI: 10.1038/nnano.2015.342, in press 国立大学法人東京大学
107 H. Nishida, Y. Matsumoto, K. Kawana, R. J. Christie, M. Naito, B. -S. Kim, K. Toh, H. -S. Min, Y. Yi, Y. Matsumoto, H. -J. Kim, K. Miyata, A. Taguchi, K. Tomio, A. Yamashita, T. Inoue, H. Nakamura, A. Fujimoto, M. Sato, M. Yoshida, K. Adachi, T. Arimoto, O. WadaHiraike, K. Oda, T. Nagamatsu, N. Nishiyama, K. Kataoka, Y. Osuga, T. Fujii, Systemic delivery of siRNA by actively targeted polyion complex micelles for silencing the E6 and E7 human papillomavirus oncogenes, J. Control. Release, DOI: 10.1016/j.jconrel.2016.03.016, in press 国立大学法人東京大学
108 Y. Matsumoto, Y. Miyamoto, H. Cabral, Y. Matsumoto, K. Nagasaka, S. Nakagawa, D. Maeda, T. Yano, K. Oda, K. Kawana, N. Nishiyama, K. Kataoka, T. Fujii, Enhanced efficacy against cervical carcinomas through polymeric micelles physically incorporating the proteasome inhibitor MG132, Cancer Sci., DOI: 10.1111/cas.12926, in press 国立大学法人東京大学
109 T. Nomoto, S. Fukushima, M. Kumagai, K. Miyazaki, A. Inoue, P. Mi, Y. Maeda, K. Toh, Y. Matsumoto, Y. Morimoto, A. Kishimura, N. Nishiyama, K. Kataoka, Calcium phosphate-based organic–inorganic hybrid nanocarriers with pH-responsive on/off switch for photodynamic therapy, Biomater. Sci., DOI: 10.1039/C6BM00011H, in press 国立大学法人東京大学

その他(総説・図書）

No. 発行・著者名 書籍名 発行年月
1 千代田テクノエース　須藤 芳彦 『近代建築』　2015年5月　Vol.69 P.73-78 ナノ医療イノベーションセンター 2015年5月
2 公益財団法人川崎市産業振興財団 Newsletter NanoSky vol.1（日本語版）
体内病院が描く未来の姿		 2016年3月

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