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論文・その他(図書・総説） 2016年度

論文　|　その他(総説・図書）

論文

No. タイトル・発表者等 発表機関
1 D. L. Stirland, Y. Matsumoto, K. Toh, K. Kataoka, Y. -H. Bae, Analyzing spatiotemporal distribution of uniquely fluorescent nanoparticles in xenograft tumors, J. Control. Release, 227, 38-44, doi: 10.1016/j.jconrel.2016.02.016, 2016. 東京大学
ナノ医療イノベーションセンター
2 S. Florinas, M. Liu, R. Fleming, L. V. V.-Ysla, J. Ayriss, R. Gilbreth, N. Dimasi, C. Gao, H. Wu, Z.-Q. Xu, S. Chen, A. Dirisala, K. Kataoka, H. Cabral, R. J. Christie, A Nanoparticle platform to evaluate bioconjugation and receptor-mediated cell uptake using crosslinked polyion complex micelles bearing antibody fragments, Biomacromolecules, 17, 1818-1833, doi: 10.1021/acs.biomac.6b00239, 2016. 東京大学
ナノ医療イノベーションセンター
3 M. Wang, Y. Miura, K. Tsuchihashi, K. Miyano, O. Nagano, M. Yoshikawa, A. Tanabe, J. Makino, Y. Mochida, N. Nishiyama, H. Saya, H. Cabral, K. Kataoka, Eradication of CD44-variant positive population in head and neck tumors through controlled intracellular navigation of cisplatin-loaded nanomedicines, J. Control. Release, 230, 26-33, doi: 10.1016/j.jconrel.2016.03.038, 2016. 東京大学
ナノ医療イノベーションセンター
4 F. Perche, Y. Yi, L. Hespel, P. Mi, A. Dirisala, H. Cabral, K. Miyata, K. Kataoka, Hydroxychloroquine-conjugated gold nanoparticles for improved siRNA activity, Biomaterials, 90, 62-71, doi: 10.1016/j.biomaterials.2016.02.027, 2016. 東京大学
ナノ医療イノベーションセンター
5 R. Taniguchi, Y. Miura, H. Koyama, T. Chida, Y. Anraku, A. Kishimura, K. Shigematsu, K. Kataoka, T. Watanabe, Adequately-sized nanocarriers allow sustained targeted drug delivery to neointimal lesions in rat arteries, Mol. Pharmaceutics, 13, 2108-2116, doi: 10.1021/acs.molpharmaceut.6b00219, 2016. 東京大学
ナノ医療イノベーションセンター
6 Y. Matsumoto, J. W. Nichols, K. Toh, T. Nomoto, H. Cabral, Y. Miura, R. J. Christie, N. Yamada, T. Ogura, M. R. Kano, Y. Matsumura, N. Nishiyama, T. Yamasoba, Y. -H. Bae, K. Kataoka, Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery, Nat. Nanotechnol., 11, 533-538, doi: 10.1038/nnano.2015.342, 2016. 東京大学
ナノ医療イノベーションセンター
7 Y. Matsumoto, Y. Miyamoto, H. Cabral, Y. Matsumoto, K. Nagasaka, S. Nakagawa, D. Maeda, T. Yano, K. Oda, K. Kawana, N. Nishiyama, K. Kataoka, T. Fujii, Enhanced efficacy against cervical carcinomas through polymeric micelles physically incorporating the proteasome inhibitor MG132, Cancer Sci., 107, 773-781, doi: 10.1111/cas.12926, 2016. 東京大学
ナノ医療イノベーションセンター
8 H. Nishida, Y. Matsumoto, K. Kawana, R. J. Christie, M. Naito, B. -S. Kim, K. Toh, H. -S. Min, Y. Yi, Y. Matsumoto, H. -J. Kim, K. Miyata, A. Taguchi, K. Tomio, A. Yamashita, T. Inoue, H. Nakamura, A. Fujimoto, M. Sato, M. Yoshida, K. Adachi, T. Arimoto, O. WadaHiraike, K. Oda, T. Nagamatsu, N. Nishiyama, K. Kataoka, Y. Osuga, T. Fujii, Systemic delivery of siRNA by actively targeted polyion complex micelles for silencing the E6 and E7 human papillomavirus oncogenes, J. Control. Release, 231, 29-37, doi: 10.1016/j.jconrel.2016.03.016, 2016. 東京大学
ナノ医療イノベーションセンター
9 T. Shirasu, H. Koyama, Y. Miura, K. Hoshina, K. Kataoka, T. Watanabe, Nanoparticles effectively target rapamycin delivery to sites of experimental aortic aneurysm in rats, PLOS ONE, 11(6), e0157813, doi: 10.1371/journal.pone.0157813, 2016. 東京大学
ナノ医療イノベーションセンター
10 H. Kinoh, Y. Miura, T. Chida, X. Liu, K. Mizuno, S. Fukushima, Y. Morodomi, N. Nishiyama, H. Cabral, K. Kataoka, Nanomedicines eradicating cancer stem-like cells in vivo by pH-triggered intracellular cooperative action of loaded drugs, ACS Nano, 10, 5643-5655, doi: 10.1021/acsnano.6b00900, 2016. 東京大学
ナノ医療イノベーションセンター
11 R. N. Gilbreth, S. Novarra, L. Wetzel, S. Florinas, H. Cabral, K. Kataoka, J. RiosDoria, R. J. Christie, M. Baca, Lipid- and polyion complex-based micelles as agonist platforms for TNFR superfamily receptors, J. Control. Release, 234, 104-114, doi: 10.1016/j.jconrel.2016.05.041, 2016. 東京大学
ナノ医療イノベーションセンター
12 Y. Takeuchi, N. Yahagi, Y. Aita, Y. Murayama, Y. Sawada, X. Piao, N. Toya, Y. Oya, A. Shikama, A. Takarada, Y. Masuda, M. Nishi, M. Kubota, Y. Izumida, T. Yamamoto, M. Sekiya, T. Matsuzaka, Y. Nakagawa, O. Urayama, Y. Kawakami, Y. Iizuka, T. Gotoda, K. Itaka, K. Kataoka, R. Nagai, T. Kadowaki, N. Yamada, Y. Lu, M. K. Jain, H. Shimano, KLF15 enables rapid switching between lipogenesis and gluconeogenesis during fasting, Cell Rep., 16, 2373-2386, doi: 10.1016/j.celrep.2016.07.069, 2016. ナノ医療イノベーションセンター
13 S. Kikuta, Y. Matsumoto, A. Kuboki, T. Nakayama, D. Asaka, N. Otori, H. Kojima, T. Sakamoto, A. Kashio, K. Kanaya, R. Ueha, R. Kagoya, H. Nishijima, M. Toma-Hirano, Y. Kikkawa, K. Kondo, K. Tsunoda, T. Miyaji, T. Yamaguchi, K. Kataoka, K. Mori, T. Yamasoba, Longer latency of sensory response to intravenous odor injection predicts olfactory neural disorder, Sci. Rep., 6, Online Only, doi: 10.1038/srep35361, 2016. ナノ医療イノベーションセンター
14 Q. Chen, K. Osada, Z. Ge, S. Uchida, T. A. Tockary, A. Dirisala, A. Matsui, K. Toh, K. M. Takeda, X. Liu, T. Nomoto, T. Ishii, M. Oba, Y. Matsumoto, K. Kataoka, Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting, Biomaterials, 113, 253-265, doi: 10.1016/j.biomaterials.2016.10.042, 2016. 東京大学
ナノ医療イノベーションセンター
15 K. Katsushima, A. Natsume, F. Ohta, K. Shinjo, A. Hatanaka, N. Ichimura, S. Sato, S. Takahashi, H. Kimura, Y. Totoki, T. Shibata, M. Naito, H. -J. Kim, K. Miyata, K. Kataoka, Y. Kondo, Targeting the notch-regulated non-coding RNA TUG1 for glioma treatment, Nat. Commun., 7, Online Only, doi: 10.1038/ncomms13616, 2016. 東京大学
ナノ医療イノベーションセンター
16 Y. Yi, H. J. Kim, P. Mi, M. Zheng, H. Takemoto, K. Toh, B. S. Kim, K. Hayashi, M. Naito, Y. Matsumoto, K. Miyata, K. Kataoka, Targeted systemic delivery of siRNA to cervical cancer model using cyclic RGD-installed unimer polyion complex-assembled gold nanoparticles, J. Control. Release The 14th edition of the European Symposium on Controlled Drug Delivery, Egmond aan Zee, The Netherlands on April 13-15, 2016, 244, 247-256, doi: 10.1016/j.jconrel.2016.08.041, 2016. 東京大学
ナノ医療イノベーションセンター
17 S. Osawa, T. Ishii, H. Takemoto, K. Osada, K. Kataoka, A facile amino-functionalization of poly(2-oxazoline)s’ distal end through sequential azido end-capping and Staudinger reactions, Eur. Polym. J., 88, 553-561, doi: 10.1016/j.eurpolymj.2016.11.029, 2017. 東京大学
ナノ医療イノベーションセンター
18 K. M. Takeda, Y. Yamasaki, A. Dirisala, S. Ikeda, T. A. Tockary, K. Toh, K. Osada, K. Kataoka, Effect of shear stress on structure and function of polyplex micelles from poly(ethylene glycol)-poly(L-lysine) block copolymers as systemic gene delivery carrier, Biomaterials, 126, 31-38, doi: 10.1016/j.biomaterials.2017.02.012, 2017. 東京大学
ナノ医療イノベーションセンター
19 M. Naito, R. Azuma, H. Takemoto, M. Hori, N. Yoshinaga, S. Osawa, R. Kamegawa, H. -J. Kim, T. Ishii, N. Nishiyama, K. Miyata, K. Kataoka, Multilayered polyion complexes with dissolvable silica layer covered by controlling densities of cRGD-conjugated PEG chains for cancer-targeted siRNA delivery, J. Biomater. Sci. Polym. Ed., doi: 10.1080/09205063.2017.1301775, in press 東京大学
ナノ医療イノベーションセンター
20 P. Mi, D. Kokuryo, H. Cabral, H. Wu, Y. Terada, T. Saga, I. Aoki, N. Nishiyama, K. Kataoka, A pH-activatable nanoparticle with signal-amplification capabilities for non-invasive imaging of tumour malignancy, Nat. Nanotechnol., 11, 724-730, doi: 10.1038/nnano.2016.72, 2016. ナノ医療イノベーションセンター、東京大学、東京工業大学、量研機構・放医研
21 K. M. Takeda, K. Osada, T. A. Tockary, A. Dirisala, Q. Chen, K. Kataoka, Poly(ethylene glycol) crowding as critical factor to determine pDNA packaging scheme into polyplex micelles for enhanced gene expression, Biomacromolecules, 18, 36-43, doi: 10.1021/acs.biomac.6b01247, 2017. ナノ医療イノベーションセンター、東京大学
22 P. Mi, H. Yanagie, N. Dewi, H.-C. Yen, X. Liu, M. Suzuki, Y. Sakurai, K. Ono, H. Takahashi, H. Cabral, K. Kataoka, Block copolymer-boron cluster conjugate for effective boron neutron capture therapy of solid tumors, J. Control. Release, doi: 10.1016/j.jconrel.2017.03.036, in press. ナノ医療イノベーションセンター、東京大学、東京工業大学
23 Sugaya A, Hyodo I, Koga Y, Yamamoto Y, Takashima H, Sato R, Tsumura R, Furuya F, Yasunaga M, Harada M, Tanaka R, Matsumura Y. Utility of epirubicin-incorporating micelle tagged with anti-tissue factor antibody clone with no anticoagulant effect. Cancer Sci. 107(3):335-340, 2016. 国立がん研究センター
ナノキャリア
24 N. Sasaki, M. Tatanou, T. Suzuki, Y. Anraku, A. Kishimura, K. Kataoka, K. Sato, A membrane-integrated microfluidic device to study permeation of nanoparticles through straight micropores toward rational design of nanomedicines, Anal. Sci., 32, 1307-1314, doi: 10.2116/analsci.32.1307, 2016. 東京大学
ナノ医療イノベーションセンター
25 K. M. Takeda, K. Osada, T. A. Tockary, A. Dirisala, Q. Chen, K. Kataoka, Poly(ethylene glycol) crowding as critical factor to determine pDNA packaging scheme into polyplex micelles for enhanced gene expression, Biomacromolecules, 18, 36-43, doi: 10.1021/acs.biomac.6b01247, 2017. 東京大学
ナノ医療イノベーションセンター
26 D. Sueyoshi, Y. Anraku, T. Komatsu, Y. Urano, K. Kataoka, Enzyme-loaded polyion complex vesicles as in vivo nanoreactors working sustainably under the blood circulation: Characterization and functional evaluation, Biomacromolecules, doi: 10.1021/acs.biomac.6b01870, in press 東京大学
ナノ医療イノベーションセンター
27 A. Goto, H.-C. Yen, Y. Anraku, S. Fukushima, P.-S. Lai, M. Kato, A. Kishimura, K. Kataoka, Facile preparation of delivery platform of water-soluble low-molecular-weight drugs based on polyion complex vesicle (PICsome) encapsulating mesoporous silica nanoparticle, ACS Biomater. Sci. Eng., doi: 10.1021/acsbiomaterials.6b00562, in press 東京大学
ナノ医療イノベーションセンター
28 F. Perche, S. Uchida, H. Akiba, C.-Y. Lin, M. Ikegami, A. Disrala, T. Nakashima, K. Itaka, K. Tsumoto, K. Kataoka, Improved brain expression of anti-amyloid β scFv by complexation of mRNA including a secretion sequence with PEG-based block catiomer, Curr. Alzheimer Res., 14, 295-302, doi: 10.2174/1567205013666161108110031, 2017. ナノ医療イノベーションセンター、東京大学
29 A. Goto, H.-C. Yen, Y. Anraku, S. Fukushima, P.-S. Lai, M. Kato, A. Kishimura, K. Kataoka, Facile preparation of delivery platform of water-soluble low-molecular-weight drugs based on polyion complex vesicle (PICsome) encapsulating mesoporous silica nanoparticle, ACS Biomater. Sci. Eng., doi: 10.1021/acsbiomaterials.6b00562, in press. ナノ医療イノベーションセンター、東京大学
30 Anraku Y, Kuwahara H, Fukusato Y, Mizoguchi A, Ishii T, Nitta K, Matsumoto Y, Toh K, Miyata K, Uchida S, Nishina K, Osada K, Itaka K, Nishiyama N, Mizusawa H, Yamasoba T, Yokota T, Kataoka T. Crossing the BBB: Glycemic control boosts glucosylated nanocarrier transport into brain. Nat commun. 東京大学、東京医科歯科大学
31 横田隆徳、仁科一隆、桑原宏哉．核酸医薬を用いた遺伝子治療の展望. 神経治療学33(3): 303-306, 2016. 東京医科歯科大学
32 C.-Y. Lin, F. Perche, M. Ikegami, S. Uchida, K. Kataoka, K. Itaka, Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polyplex nanomicelles, J. Control. Release, 235, 268-275, doi: 10.1016/j.jconrel.2016.06.001, 2016. 東京大学
ナノ医療イノベーションセンター
33 S. Uchida, K. Hayakawa, T. Ogata, S. Tanaka, K. Kataoka, K. Itaka, Treatment of spinal cord injury by an advanced cell transplantation technology using brain-derived neurotrophic factor-transfected mesenchymal stem cell spheroids, Biomaterials, 109, 1-11, doi: 10.1016/j.biomaterials.2016.09.007, 2016. 東京大学
ナノ医療イノベーションセンター
34 Komaki, Y., Hikishima, K., Shibata, S., Komaki, T., Seki, F., Ymada, M., Miyasaka, N., Fujiyoshi, K., Okano, H.J., Nakamura, M. and Okano, H., : Functiomal brain mapping using specific sensory-circuit stimulation and a theoretical graph network analysis in mice with neuropathic allodynia. Scientific Report, 2016, Nov., 29;6:37802. 実験動物中央研究所
35 A. Nagaoka, H. Takehara, A. Hayashi-Takagi, J. Noguchi, K. Ishii, S. Yagishita, T. Akagi, T. Ichiki and H. Kasai, “Abnormal intrinsic turnovers of dendritic spines in fragile-X mice”, Sci. Rep. 6, 26651 (2016). 東京大学
36 Hiroaki Takehara, Akira Nagaoka, Jun Noguchi, Takanori Akagi, Haruo Kasai, and Takanori Ichiki,
“Implantable microfluidic device with hydrogel permeable membrane for delivering chemical compounds and imaging neural cells in living mice”, Journal of Photopolymer Science and Technology (2016).		 東京大学
37 T. Akagi and T. Ichiki, “Characterization of EVs by on-chip Immunoelectrophoresis", Extracellular Vesicles: Methods and Protocols (accepted). 東京大学
38 Isokawa, M., Y. Kanbayashi, K. Nomura, D. Iwahata, T. Mizukoshi, N. Yamada, H. Miyano, T. Funatsu, and M. Tsunoda, Determination and characterization of total thiols in mouse serum samples using hydrophilic interaction liquid chromatography with fluorescence detection and mass spectrometry, J. Chromatogr. B. 1019, 59-65, doi: 10.1016/j.jchromb.2015.11.038, 2016. 東京大学
39 Ito, N., E. Yamamoto, T. Santa, T. Funatsu, and M. Kato, Effect of nanoparticle surface on the HPLC elution profile of liposomal nanoparticles, Pharm. Res., 33 (6), 1440-1446, doi: 10.1007/s11095-016-1886-4, 2016. 東京大学
40 Hattori, K., I. Naguro, K. Okabe, T. Funatsu, S. Furutani, K. Takeda, and H. Ichijo, ASK1 signaling regulates brown and beige adipocyte function, Nat. Commun. 7, 11158, doi: 10.1038/ncomms11158, 2016. 東京大学
41 Sakamoto, A., T. Tsukamoto, Y. Furutani, Y. Sudo, K. Shimada, A. Tomita, H. Kiyoi, T. Kato, and T. Funatsu, Live-cell single-molecule imaging of the cytokine receptor MPL for analysis of dynamic dimerization. J. Mol. Cell Biol. 8(6), 553-555, doi: 10.1093/jmcb/mjw027, 2016. 東京大学
42 Kanamori, T., T. Funatsu, and M. Tsunoda, Determination of catecholamines and related compounds in mouse urine using column-switching HPLC, Analyst. 141, 2568-2573, doi: 10.1039/c5an02617b, 2016. 東京大学
43 Song, Y., K. Takatsuki, T. Sekiguchi, T. Funatsu, S. Shoji, M. Tsunoda, Rapid quantitative method for the detection of phenylalanine and tyrosine in human plasma using pillar array columns and gradient elution, Amino Acids. 48, 1731-1735, doi: 10.1007/s00726-016-2248-6, 2016. 東京大学
44 Iizuka, R. and T. Funatsu, Chaperonin GroEL uses asymmetric and symmetric reaction cycles in response to the concentration of non-native substrate proteins, Biophys. Physicobiol. 13, 63-69, doi: 10.2142/biophysico.13.0_63, 2016. 東京大学
45 Isokawa, M., K.Takatsuki, Y. Song, K. Shih, K. Nakanishi, Z. Xie, D. H. Yoon, T. Sekiguchi, T. Funatsu, S. Shoji, M. Tsunoda, Liquid chromatography chip with low-dispersion and low-pressure-drop turn structure utilizing a distribution-controlled pillar array, Anal. Chem. 88, 6485-6491, doi: 10.1021/acs.analchem.6b01201, 2016. 東京大学
46 Song, Y., K. Takatsuki, T. Sekiguchi, T. Funatsu, S. Shoji, and M. Tsunoda, Retention and bandwidth predictions by fast gradient elutionchromatography using a pillar array column, Chromatography, 37, 111-116, doi: 10.15583/jpchrom.2016.008, 2016. 東京大学
47 M. Isokawa, K. Kobayashi, Y. Miyoshi, M. Mita, T. Funatsu, K. Hamase, M. Tsunoda, Quantification of Biological Thiols in the Plasma of a Homocystinuria Model with Cystathionine β-Synthase Deficiency Utilizing Hydrophilic Interaction Liquid Chromatography and Fluorescence Detection. Chromatography, 37, 147-151, doi: 10.15583/jpchrom.2016.015, 2016. 東京大学
48 Amamoto, T., S. Hirakawa, T. Santa, T. Funatsu, and M. Kato, Surface modification of silica nanoparticles with 4-aryloxy boron dipyrromethene (BODIPY) enhances skin permeation, J. Mater. Chem. B,  4, 7676-7680, doi: pubs.rsc.org/en/Content/ArticlePDF/2014/CC/c4cc03168g, 2016. 東京大学
49 Itoh, N., A. Kimoto, E. Yamamoto, T. Higashi, T. Santa, T. Funatsu, and M. Kato, High performance liquid chromatography analysis of 100-nm liposomal nanoparticles using polymer-coated, silica monolithic columns with aqueous mobile phase, Journal of Chromatography A. 1484, 34-40, doi: 10.1016/j.chroma.2016.12.080, 2017. 東京大学
50 Yokoi A, Yoshioka Y, Yamamoto Y, Ishikawa M, Ikeda SI, Kato T, Kiyono T, Takeshita F, Kajiyama H, Kikkawa F, Ochiya T. Malignant extracellular vesicles carrying MMP1 mRNA facilitate peritoneal dissemination in ovarian cancer. Nat Commun. 8:14470. 2017 国立がん研究センター
51  Somiya M, Yoshioka Y, Ochiya T. Drug delivery application of extracellular vesicles; insight into production, drug loading, targeting, and pharmacokinetics. AIMS Bioengineering, 4(1): 73-92. 2017 国立がん研究センター
52 Yoshimura A, Kawamata M, Yoshioka Y, Katsuda T, Kikuchi H, Nagai Y, Adachi N, Numakawa T, Kunugi H, Ochiya T, Tamai Y. Generation of a novel transgenic rat model for tracing extracellular vesicles in body fluids. Sci Rep. 6:31172. 2016 国立がん研究センター
53 Kosaka N, Yoshioka Y, Fujita Y, Ochiya T. Versatile roles of extracellular vesicles in cancer. J Clin Invest. 126(4):1163-72. 2016 国立がん研究センター
54 Miyuki Tabata, Chindanai Ratanaporncharoen, Aoi Asano, Yuichi Kitasako, Masaomi Ikeda, Tatsuro Goda, Akira Matsumoto, Junji Tagami, Yuji Miyahara,
"Miniaturized Ir/IrOx pH Sensor for Quantitative Diagnosis of Dental Caries",
Procedia Eng., 2016, 168, 598-601. DOI: 10.1016/j.proeng.2016.11.223.		 東京医科歯科大学
55 Miyuki Tabata, Yurika Katayama, Fahmida Mannan, Ayaka Seichi, Koji Suzuki, Tatsuro Goda, Akira Matsumoto, Yuji Miyahara,
"Label-free and Electrochemial Detection of Nucleic Acids Based on Isothermal Amplification in Combination with Solid-state pH Sensor",
Procedia Eng., 2016, 168, 419-422. DOI: 10.1016/j.proeng.2016.11.534. 		 東京医科歯科大学
56 Kazuki Hasegawa, Rina Negishi, Mutsuyoshi Matsumoto, Masafumi Yohda, Kazuo Hosokawa, Mizuo Maeda; Specificity of microRNA detection on a power-free microfluidic chip with laminar flow-assisted dendritic amplification, Analytical Sciences, 33, 171-177, 2017 理化学研究所
57 Ryo Ishihara, Yoshitaka Uchino, Kazuo Hosokawa, Mizuo Maeda, Akihiko Kikuchi, Preparation of a surface-functionalized power-free PDMS microchip for microRNA detection utilizing electron beam-induced graft polymerization, Analytical Sciences, 33, 197-202, 2017 理化学研究所
58 SangWook Lee, Kazuo Hosokawa, Soyoun Kim, Ok Chan Jeong, Hans Lilja, Thomas Laurell, Mizuo Maeda; Porous silicon microarray for simultaneous fluorometric immunoassay of the biomarkers prostate-specific antigen and human glandular kallikrein 2, Microchimica Acta, 183, 3321-3327, 2016 理化学研究所
59 Kazuki Hasegawa, Mutsuyoshi Matsumoto, Kazuo Hosokawa, Mizuo Maeda; Detection of methylated DNA on a power-free microfluidic chip with laminar flow-assisted dendritic amplification, Analytical Sciences, 32, 603-606, 2016 理化学研究所
60 T. Nomoto, S. Fukushima, M. Kumagai, K. Miyazaki, A. Inoue, P. Mi, Y. Maeda, K. Toh, Y. Matsumoto, Y. Morimoto, A. Kishimura, N. Nishiyama, K. Kataoka, Calcium phosphate-based organic–inorganic hybrid nanocarriers with pH-responsive on/off switch for photodynamic therapy, Biomater. Sci., 4, 826-838, doi: 10.1039/C6BM00011H, 2016. 東京工業大学
ナノ医療イノベーションセンター
61 H. Hino, M. Kamiya, K. Kitano, K. Mizuno, S. Tanaka, N. Nishiyama, K. Kataoka, Y. Urano, J. Nakajima, Rapid cancer fluorescence imaging using a γ-glutamyltranspeptidase-specific probe for primary lung cancer, 9, 203-210, doi: 10.1016/j.tranon.2016.03.007, 2016. 東京工業大学
ナノ医療イノベーションセンター
62 M. Iijima, D. Ulkoski, S. Sakuma, D. Matsukuma, N. Nishiyama, H. Otsuka, C. Scholz, Synthesis of PEGylated poly(amino acid) pentablock copolymers and their self-assembly. Polymer International 65 (10) 1132-1141 (2016) (DOI: 10.1002/pi.5159) 東京工業大学
63 N. F. Che Harun, H. Takemoto, T. Nomoto, K. Tomoda, M. Matsui, N. Nishiyama, Artificial control of gene silencing activity based on siRNA conjugation with polymeric molecule having coil–globule transition behavior. Bioconjugate Chem. 27 (9) 1961-1964 (2016) (DOI: 10.1021/acs.bioconjchem.6b00322) 東京工業大学
64 C. H. Huang, H. Takemoto, T. Nomoto, K. Tomoda, M. Matsui, N. Nishiyama, Utility of the 2-nitrobenzenesulfonamide group as a chemical linker for enhanced extracellular stability and cytosolic cleavage in siRNA-conjugated polymer systems. ChemMedChem 12 (1) 19-22 (2017) (DOI: 10.1002/cmdc.201600488) 東京工業大学
65 Sakamoto,W. ,  Ochiai,T.,  Shimada, N. and  Maruyama,A. Cationic copolymer augments membrane permeabilizing activity of an amphiphilic peptide J BIOMAT SCI-POLYM E.in press, 2017  東京工業大学
66 Shimada,N., Saito, M.,  Shukuri, S.,  Kuroyanagi, S.,  Kuboki, T., Kidoaki,S., Nagai, T., and Maruyama,A. Reversible Monolayer/Spheroid Cell Culture Switching by UCST-Type Thermoresponsive Ureido Polymers, ACS Appl. Mater. Inter. 8, 31524-31529. doi:10.1021/acsami.6b076142016   東京工業大学
67 Saito,K., Shimada,N. and Maruyama, A.,  Cooperative enhancement of deoxyribozyme activity by chemical modification and added cationic copolymer, Sci. Tech. Adv. Mater. 17,437-442. doi: 10.1080/14686996.2016.12086272016 東京工業大学
68 Fujihara, A.,  Itsuki, K.,  Shimada,N.,  Maruyama, A.,  Sagawa, N., Shikata, T. ,  Yusa, S., Preparation of Ureido Group Bearing Polymers and Their Upper Critical Solution Temperature in Water, J. Polym. Sci., Polym. Chem. 54, 2845-2854. doi: 10.1002/pola.2818, 2016 東京工業大学
69 Liu, Q., Somiya,M.,  Shimada, N.,  Sakamoto,W., Yoshimoto, N.,  Iijima, M., Tatematsu, K., Nakai, T.,  Okajima,  T.,  Maruyama, A.,  Kuroda, S.,  Mutational analysis of hepatitis B virus pre-S1 (9–24) fusogenic peptide, Biochem. Biophys. Res. Commun., 474, 406-412, oi: 10.1016/j.bbrc.2016.04.125., 2016 東京工業大学
70 Araki T, Murayama S, Usui K, Shimada T, Aoki I, Karasawa S. Self-Assembly Behavior of Emissive Urea Benzene Derivatives Enables Heat-Induced Accumulation in Tumor Tissue. Nano Lett. 2017 Mar 7. doi: 10.1021/acs.nanolett.6b05371. [Epub ahead of print] PubMed PMID: 28264561. 量研機構・放医研
71 Sawada K, Fukunishi K, Kashima M, Imai N, Saito S, Aoki I, Fukui Y. Regional difference in sulcal infolding progression correlated with cerebral cortical expansion in cynomolgus monkey fetuses. Congenit Anom (Kyoto). 2017 Jan 21. doi:10.1111/cga.12209. [Epub ahead of print] PubMed PMID: 28109019. 量研機構・放医研
72 Aoki I. Nano-theranostics and Nitroxyl Radical-labeled Antitumor Agents for Magnetic Resonance Imaging. Yakugaku Zasshi. 2016;136(8):1087-91. doi:10.1248/yakushi.15-00234-3. PubMed PMID: 27477722. 量研機構・放医研
73 Atanasova S, Nikolova B, Murayama S, Stoyanova E, Tsoneva I, Zhelev Z, Aoki I, Bakalova R. Electroinduced Delivery of Hydrogel Nanoparticles in Colon 26 Cells, Visualized by Confocal Fluorescence System. Anticancer Res. 2016 Sep;36(9):4601-6. PubMed PMID: 27630301. 量研機構・放医研
74 Morishita K, Murayama S, Araki T,  Aoki I, Karasawa S.Thermal- and pH-Dependent Size Variable Radical Nano-particles and Its Water Proton Relaxivity for Metal-free MRI Functional Contrast Agents. J. Org. Chem. 2016 Aug; 81(18):8351-62. PubMed PMID:   27541011  量研機構・放医研
75 安西智宏、「日本外科学会定期学術集会　「NCDの活用ーデバイスラグの解消に向けてー　製品開発・承認・市販後における大規模臨床データベースの有用性」」　日本外科学誌　117(5): 468-470, 2016 東京大学
東京工業大学
76 Anzai, T., Sengoku, S., Managing Academic Interdisciplinary Research towards Innovation: A Resource and Communication-Based Approach, Technology Transfer and Entrepreneurship, 3(2), 70-81 (2016) 東京大学
東京工業大学

その他(総説・図書）

No. 発行・著者名 書籍名 発行年月
1 公益財団法人川崎市産業振興財団 産業情報　かわさき　2016年6月号 2016年6月
2 公益財団法人川崎市産業振興財団 Newsletter NanoSky vol.1（英語版）
COINS A Future Created by "In-Body Hospital"		 2016年7月
3 公益財団法人川崎市産業振興財団 Newsletter NanoSky vol.2（日本語版）
がん治療をかえるナノマシン		 2016年12月
4 公益財団法人川崎市産業振興財団 Newsletter NanoSky vol.2（英語版）
Nanomachines Changing Cancer Treatment		 2017年3月
5 公益財団法人川崎市産業振興財団 Newsletter NanoSky vol.3（日本語版）
ナノ診断技術が変わる未来の医療		 2017年3月

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