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COINS Seminar #10 & #11 were held on Friday, November 27 at iCONM. Dr.Muthiah Manoharan, Senior Vice President of Innovation Chemistry and Distinguished Scientist at Alnylam Pharmaceuticals,USA gave us a lecture titled "Chemistry of Therapeutic Oligonucleotides: An Overview"and Dr.Sai Kiang Lim, Research Director, A*STAR Institute of Medical Biology, Singapore gave us a lecture titled "The whats, whys and hows of Extracellular Vesicles"There was a lively discussion as well. We thank everyone who took the time out to attend the seminar. Please go to the leaflet（#10 & #11） for more details.